Issue 186
C&T Round Up for July 2022!
This week, we highlight the feature articles we published in July! Learn about Intralytix's past and present, navigating complexity when you start making phages for therapy, and the new phage-bacteria interaction atlas the Gates Foundation is funding.
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PHAGE Journal is now indexed in PubMed Central and Scopus! The journal invites you to submit your manuscript for online publication.
Community digest5updates8jobs2posts
Updates
Paper: Comparative genomics of Acinetobacter baumannii and therapeutic bacteriophages from a patient undergoing phage therapy. (A follow-up on the Patterson case!)
Paper: Cell-free production of personalized therapeutic phages targeting multidrug-resistant bacteria.
Paper: Transplantation of bacteriophages from ulcerative colitis patients shifts the gut bacteriome and exacerbates the severity of DSS colitis.
Paper: Anti-CRISPR prediction using deep learning reveals an inhibitor of Cas13b nucleases.
Paper: Phage long tail fiber protein-immobilized magnetic nanoparticles for rapid and ultrasensitive detection of Salmonella.
Jobs
Several positions: at the Gurney lab at GSU in Atlanta, Georgia. Interested in working on phage coevolution and phage therapy? Hiring grad students (funded 5 yr), research tech (3 yr), and a 2 year funded postdoc. Send Dr. Gurney your CV and personal statement. Subject line GurneyLab: Jamesrgurney@gmail.com.
Postdoc: Interested in applying computational approaches to address translational questions in infectious diseases? We're recruiting a postdoc to work on studies involving phages and cfDNA. — Paul Bollyky on Twitter
PhD Fellowship in Microbiology in bacteria-phage interaction at University of Copenhagen.
PhD project: Longitudinal carriage of temperate phages of Pseudomonas aeruginosa and their role in the chronically infected lung at Northumbria University.
Doctoral Researcher within the Academy of Finland research project "Ecology of bacteriophages in mucosa during vertebrate host lifespan" at University of Jyväskylä.
Research Scientist to join the Laboratory of Dr Evelien Adriaenssens in the Gut Microbes and Health Programme at Quadram Institute Bioscience (QIB), based in Norwich, UK.
Postdoctoral Fellowship in phage microbiology with CSIRO in Tasmania, Australia.
PhD position to study infection mechanisms of archaeal viruses at University of Groningen.
Community board
Never miss another phage event or deadline — you can now subscribe to Phage Calendar! Thanks to Sayde Perry, one of our star Phage Directory volunteers, for setting it up!
Subscribe to the Google calendar here.
If you use iCal, add it to your calendar with this .ics file.
Currently we’re adding conferences and deadlines to register for phage-related events and beyond. If you have anything you’d like to add to the calendar, fill out this form — please include the name, date(s), URL and optional short description.
Register to attend The Phage Canada Virtual Symposia 2022! This virtual event will be held August 17th - 19th and aims to promote the exchange of ideas within the phage field, provide a forum for students and postdocs to present their research and foster interactions between phage researchers. Deadline to register is Aug 13.
In this month's Capsid & Tail Monthly Round Up issue, we're highlighting the three feature articles we published in July. Be sure to check them out if you missed them, and let us know if you have thoughts, comments or questions! Reach us anytime by email!
- Intralytix: then and now, an interview with Intralytix CEO and founder Alexander Sulakvelidze, by Madhav Madurantakam Royam
- How to start making phages for therapy, a blog post on navigating complexity when setting up to make therapeutic phages, by Jessica Sacher
- Illuminating one of biology’s biggest blind spots, a blog post by Kayla Young of Phase Genomics on a phage-host interaction atlas they're building
C&T Throwback!
There's lots of great phage stuff in the C&T archive! Check out this article on phage therapy in the human gut by Sabrina Green.
Jessica Sacher, PhD
I'm a co-founder of Phage Directory and have a PhD in Microbiology from the University of Alberta (I studied Campylobacter phage biology). For Phage Directory, I help physicians find phages for their patients, and I'm always trying to find new ways to help the phage field grow (especially through connecting people and highlighting awesome stuff I see happening in the field).
I spent 2022-2024 as a postdoc in Jon Iredell's group at Westmead Institute for Medical Research in Sydney, Australia, helping get Phage Australia off the ground. I helped set up workflows for phage sourcing, biobanking, diagnostics, production, purification and QC of therapeutic phage batches, and helped build data collection systems to track everything we did. We treated more than a dozen patients in our first year, and I'm so proud of that!
As of 2024, I joined the Bollyky lab at Stanford University as a Staff Scientist, where I'm focused on phage engineering and delivery (to both microbial and human cells) and hydrogel-embedded phage cocktail development for wounds!