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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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  1. Therapy studies

    Safety and Efficacy of Oral Administration of the Phage Cocktail, VRELysin™, In Healthy and VRE-Colonized Subjects

    Suspended. Checked 2026-10-03. The study is a first-in-human Phase 1/2a randomized, double-blind, placebo-controlled trial to assess the clinical safety and efficacy of VRELysin in healthy and VRE-colonized adults. A Phase 1/2a Double-Blind

    bacteriophagephageVREEnterococcusvancomycin
  2. Therapy studies

    Avis-PHAGEinLYON Clinic

    Recruiting. Checked 2026-10-03. Avis-PHAGEinLYON Clinic study is a single site non-interventional retrospective and prospective study, initiated by the Hospices Civils de Lyon. Population targeted are patients referred to the Hospices Civil

    bacteriophagemedical advice
  3. Therapy studies

    PHAGEinLYON Clinic Cohort Study: a Descriptive Study of Severe Infections Treated With Phage Therapy at the HCL.

    Recruiting. Checked 2026-10-03. PHAGEinLYON Clinic cohort study is a single site non-interventional retrospective and prospective study, initiated by the Hospices Civils de Lyon. Population targeted are patients with a severe infection trea

    bacteriophagesevere infection
  4. Therapy studies

    Clinical Trial to Demonstrate the Safety and Efficacy of DUOFAG®

    Status unconfirmed. Checked 2026-10-03. DUOFAG® is a phage cocktail containing bacteriophages active against Staphylococcus aureus and Pseudomonas aeruginosa. It is an investigational medicinal product for the treatment of surgical site inf

    Phage TherapyStaphylococcus aureusPseudomonas aeruginosaSurgical site infectionBacteriophageBacterial infections
  5. Therapy studies

    Bacteriophage Therapy for Methicillin-Sensitive Staphylococcus Aureus Prosthetic Joint Infection

    Active, not recruiting. Individual-case protocol. Checked 2026-10-03. This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of a bacteriophage cocktail to treat and prevent the recurrence of a methicillin-s

    Single patientBacteriophagePhage
  6. Therapy studies

    Bacteriophage Therapy in Spinal Cord Injury Patients With Bacteriuria

    Recruiting. Checked 2026-10-03. This is a Phase 1b study to assess the safety, tolerability, PK, and PD of investigational phage therapy (IP) in adults with SCI and bladder colonization (ASB). It is a single-center, randomized, double-blind

    BacteriophageBacteriuriaPhage TherapySpinal Cord InjuryIntravesicular infusionNeurogenic BladderIntermittent catheterizationRandomized clinical trial
  7. Therapy studies

    Bacteriophage Clinical Trial for Periprosthetic Joint Infection of Multidrug Resistant Pseudomonas Aeruginosa

    Expanded access. Individual-case protocol. Checked 2026-10-03. This is a single patient study (SPS) that aims to test the bacteriophage treatment as an experimental treatment on a patient suffering from chronic periprosthetic joint infectio

    Phage therapyPeriprosthetic Joint InfectionBacteriophage
  8. Therapy studies

    Bacteriophage Therapy for Morganella Morganii Prosthetic Joint Infection

    Active, not recruiting. Individual-case protocol. Checked 2026-10-03. This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of a bacteriophage drug product to treat and prevent the recurrence of a Morganell

    BacteriophagePeriprosthetic joint infectionPhage therapy
  9. Therapy studies

    Bacteriophage Therapy for Mycobacterium Abscessus Pulmonary Infection

    Invitation only. Individual-case protocol. Checked 2026-10-03. This study aims to use mycobacteriophage therapy, using identified in-vitro effective Mycobacteriophage Muddy_HRMN0052, along with combination conventional antimycobacterial the

    non-tuberculous mycobacteriabacteriophagemycobacteriophagemycobacterium abscessuspulmonary disease
  10. Therapy studies

    Safety of Combined Intravenous Antibiotic and Bacteriophage Therapy in Adults With Cystic Fibrosis and Antibiotic-Resistant Lung Infections

    Not yet recruiting. Checked 2026-10-03. This is a Phase 1, open-label, multi-center pilot study evaluating the safety and microbiological activity of intravenous (IV) bacteriophage therapy in combination with standard IV antibiotics in adul

    cystic fibrosisCFPhagebacteriophage
  11. Therapy studies

    Bacteriophage Therapy for Staphylococcus Lugdunensis Prosthetic Joint Infection

    Not yet recruiting. Individual-case protocol. Checked 2026-10-03. This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of a bacteriophage drug product to treat and prevent the recurrence of a Staphylococcu

    BacteriophagePeriprosthetic joint infectionPhage therapy
  12. Therapy studies

    Yiqi Huoxue Jiedu Formula Combined With Bacteriophages in the Treatment of Severe Pneumonia

    Not yet recruiting. Checked 2026-10-03. Through a prospective randomized controlled trial, we systematically evaluate the effects of Yiqi Huoxue Jiedu Formula combined with bacteriophage therapy on the bacterial clearance rate, disease impr

    bacteriophageYiqi Huoxue Jiedu Formuladrug-resistant bacteriaPneumonia
  13. Therapy studies

    "Debridement PhagE AnTibiotics for PJI"

    Not yet recruiting. Checked 2026-10-03. Total joint replacement (TJR) has revolutionized care provided for patients suffering from disabling joint pain. Unfortunately, periprosthetic joint infection (PJI) remains a devastating complication

    Phage therapyPeriprosthetic Joint InfectionBacteriophage
  14. Therapy studies

    Phage-based Control and Limitation of Pathobionts for Microbiome Equilibrium and Resilience

    Recruiting. Checked 2026-10-03. Bacteriophages are viruses that can selectively infect specific species and strains of bacteria. Some bacterial species in the human gut have been negatively associated with gut health and skin health. This s

    Gut HealthSkin HealthBacteriophage
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