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There’s a lot of improvement we can engineer into phages! Phil Huss (University of Wisconsin-Madison) and colleagues published a new paper on engineering phages using metagenomic data, showing how deep mining of metagenomic motifs can be us

Cytophage Technologies announced the development of a phage-based vaccine for avian influenza (H5N1). Two candidates that use filamentous bacteriophages to display influenza antigens are entering preclinical validation, where a pilot study

Wrapping individual phage-infected bacteria in a polymeric nanoscale coating preserves the vitality of the phages released on lysis, which otherwise have severely degraded tail proteins. In mice with bacterially induced enteritis and associ

Technology Networks feature by Blake Forman on how synthetic biology is used to modify antibiotics, improve antibiotic production and engineer more targeted phages, including CRISPR–Cas-armed phages, alongside engineered probiotics and bios

Leicester Phage is hiring a research technician to genetically engineer Salmonella-infecting bacteriophages, with the goal of developing customized phage therapeutics as alternatives to antimicrobials.

Karolinska Institutet, Solna, Sweden is hiring a postdoc to investigate phage biology and enhance phage efficacy using genetic engineering techniques.

Geeta Ram (NYU Grossman School of Medicine) and colleagues published a new paper on incorporating the gene encoding lysostaphin into their ‘Antibacterial Drone System’, showing expanded killing field and effective treatment of mixed bacteri

Jonas Fernbach (ETH Zurich) and colleagues used the PhagePromoter algorithm to identify intergenic loci in the S. aureus phage K genome for targeted payload integration, and validated their approach by engineering recombinant phages with bi

Researchers at University Medicine Rostock delivered synthetic mRNA encoding the Cpl-1 phage endolysin into three human cell lines (HEK293T, A549, HepG2), which produced endolysin with activity against Streptococcus pneumoniae. Adding a hum

Researchers at the University of Minho and partner institutions show that synthetic M13 phages displaying Aβ-derived peptides bind preferentially to amyloid-β oligomers. In hippocampus tissue from APP/PS1 transgenic mice the phages detected

Researchers at the University of California, Berkeley developed a CRISPR interference method to map gene essentiality in phages and applied it to the coliphages λ and P1, largely recapitulating the known essential genes of λ and giving new

Researchers at KIST Europe genetically modified filamentous fd phages to display shortened versions of a Cu(II)-specific peptide (HGFANVA). ICP-MS analyses showed improved Cu(II) binding by the engineered phages compared with wild-type fd,

Dr Tobias Bergmiller (Exeter University, UK) is hiring a Phage Researcher to harness the power of synthetic biology to engineer novel lytic phages.

Michael Brockhurst (University of Manchester, UK) is hiring a PhD student to engineer synthetic phages to optimize bacterial killing in phage therapy.

Eligo Bioscience, Paris, France, is hiring a Scientist - Microbial Synthetic Biology - Non-model bacteria and phage engineering.

Singapore University of Technology and Design researchers combined M13-conjugated polyethylene glycol with tungsten disulfide nanosheets to build a Phage-based Digital Biomolecular Sensor (P-DBS) for MCF-7 cancer cells. The sensor reached a

Eligo Bioscience, Paris, France, is hiring a Scientist - Microbial Synthetic Biology - Non-model bacteria and phage engineering.

The Deutschbauer Lab at LBNL, Berkeley, USA is hiring a postdoc for its BRaVE Phage Foundry to develop and apply molecular genetic tools (including barcoded transposon mutagenesis and CRISPR-Cas tools) in bacterial pathogens and phages.

Benjamin Adler and colleagues have developed a broad-spectrum phage functional genomics platform using programmable RNA-binding protein dRfxCas13d, uncovering hidden infection strategies and predicting over 90 essential genes in phage genom

University of California, Berkeley researchers report the first observation of heat-induced electrical potential generation on a virus, studying the pyroelectric properties of the M13 phage. Modifying the pVIII coat protein with different n