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Radical Numerics reports that phage variants designed with its Omnii-1 genome language model were administered to a patient with an antibiotic-resistant bacterial infection under an authorized, physician-led compassionate-use pathway, after

Prof. Andrzej Górski, head of the Bacteriophage Laboratory at the Ludwik Hirszfeld Institute of Immunology and Experimental Therapy (IIET PAS), is one of six recipients in the scientific-research category of the 33rd Prime Minister's Award.

A Science paper by Samuel J. Hobbs and Philip J. Kranzusch reports that phage prohead protease activity activates the CD-NTase enzymes of bacterial CBASS defence: the authors reconstitute CBASS recognition of phage T4 in vitro, identify cle

TattleTail is a rule-based bioinformatic pipeline for identifying canonical pyocin-encoding gene clusters in Pseudomonas aeruginosa. It targets the characteristic trpE–trpG-associated loci, combining conserved pyocin genes with exclusion of

A Nature Microbiology study from Lawrence Berkeley National Laboratory, UC Berkeley and Penn State presents a phylogeny-agnostic machine-learning framework that predicts strain-level phage–host interactions across diverse bacterial genera f

A Nature Microbiology study from ETH Zürich, University Hospital Basel, the University of Basel and the University of Lausanne presents HIDEN-SEQ (hidden Acr-enabled transposon-insertion sequencing), which systematically links viral genes t

Phage Tn-seq is a transposon-based approach to studying phage gene essentiality and engineering. Nature Microbiology

Armata Pharmaceuticals has received an additional $3.7 million in non-dilutive funds from the U.S. Department of War to support the Phase 3 programme of AP-SA02, its phage cocktail for complicated Staphylococcus aureus bacteremia. It is the

Armata Pharmaceuticals announced an oral presentation on September 21, 2026 at the 20th International Symposium on Staphylococci and Staphylococcal Infections (Banff, September 20-24) reporting that defined genetic diversity in its AP-SA02

A Nature Communications study from Stanford University and collaborators used a mouse model of established Pseudomonas aeruginosa wound infection to compare phage route, dose and frequency: topical, but not systemic, delivery reduced wound

Engineered non-pathogenic E. coli producing lytic phages protected mice against Salmonella infection in a preclinical proof-of-concept study. Nature Microbiology

This review surveys more than 80 phage bioinformatics tools for identification, assembly, annotation, taxonomy, lifestyle, defence, and host prediction. It compares sequence homology, machine learning, and foundation-model approaches, then

HEDROS outlines the four stages of its AI-driven PhageChooser platform: sampling farm water, sediment and shrimp to identify and characterise the pathogens present (the post focuses on Vibrio parahaemolyticus); AI-driven matching of isolate

Australia's Therapeutic Goods Administration says a three-year Good Manufacturing Practice exemption for the domestic manufacture of small-batch bacteriophage therapy products, used to treat an infection in a specific person or a small numb

Armata Pharmaceuticals announced a Journal of Molecular Biology paper, with Gino Cingolani's group at UAB, presenting a cryo-EM structural atlas of Ar-KM, a phiKMV-like phage targeting Pseudomonas aeruginosa (the AP-PA02 program). The work

Bignaud, Lamy-Besnier, Koszul, Debarbieux, Marbouty and colleagues followed the 3D organization of the virulent phage PAK_P3 genome during infection of Pseudomonas aeruginosa. The phage genome rapidly decondenses into a specific 3D organiza

Tuck Seng Wong and Kang Lan Tee (University of Sheffield) write in The Conversation that a study in which AI models designed complete bacteriophage genomes, some producing working viruses in the laboratory, shows safeguards must develop alo

Martha Clokie and Andrew Millard (University of Leicester) write in The Conversation that, after Stanford researchers used AI to design a complete ΦX174-based phage genome, the more useful question is whether AI can explain how natural phag

PBD Biotech says its Actiphage phage-based blood test, which detects live mycobacteria, can now be used to test alpacas, sheep and goats for Johne's Disease. The company says Actiphage identifies live infection from a single milk or blood s

Theraphage Lab announces Bacteriophage-Based Vectors in Gene Therapy by Roderick Slavcev, Julia Lumini, Krish Devgan, Deborah Pushparajah, Kate Nagge and Alexandra Slavcev, available from Cambridge Scholars. The book covers the use of phage