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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesOct 1, 2026

    Phage prohead proteases activate CBASS antiphage immunity (Science)

    A Science paper by Samuel J. Hobbs and Philip J. Kranzusch reports that phage prohead protease activity activates the CD-NTase enzymes of bacterial CBASS defence: the authors reconstitute CBASS recognition of phage T4 in vitro, identify cle

    UpdatesPapersPhage Biology
  2. UpdatesSep 29, 2026

    Phylogeny-agnostic machine learning predicts strain-level phage–host interactions from genomes (Nature Microbiology)

    A Nature Microbiology study from Lawrence Berkeley National Laboratory, UC Berkeley and Penn State presents a phylogeny-agnostic machine-learning framework that predicts strain-level phage–host interactions across diverse bacterial genera f

    UpdatesPapersBioinformaticsPhage Biology
  3. UpdatesSep 25, 2026

    HIDEN-SEQ: transposon-insertion sequencing that links phage genes to selectable phenotypes (Nature Microbiology)

    A Nature Microbiology study from ETH Zürich, University Hospital Basel, the University of Basel and the University of Lausanne presents HIDEN-SEQ (hidden Acr-enabled transposon-insertion sequencing), which systematically links viral genes t

    UpdatesPapersPhage GenomicsPhage Biology
  4. UpdatesSep 25, 2026

    Defining the essential genome of diverse phages with phage Tn-seq

    Phage Tn-seq is a transposon-based approach to studying phage gene essentiality and engineering. Nature Microbiology

    UpdatesPapersPhage BiologyPhage EngineeringPhage Genomics
  5. NewsSep 22, 2026

    Hynes Lab shares Ayesha Umair’s phage induction preprint

    Ayesha Umair’s first primary research preprint explores suppressing phage induction. Farncombe Phage / Hynes Lab

    NewsPhage Biology
  6. NewsSep 22, 2026

    McMaster researchers link broader-spectrum Pseudomonas phages to tail-fibre structural diversity (PNAS)

    McMaster University researchers report in PNAS that several broader-spectrum phages share particular forms of structural diversity in their tail fibres, and that the pattern held across the phages tested in Lori Burrows’ lab and dozens of s

    NewsPhage Biology
  7. NewsSep 21, 2026

    BEATS group showcases UST phage research at Phages 2026

    The University of Santo Tomas BEATS delegation presented four studies—one oral presentation and three posters—at Phages 2026 in Oxford on September 1–2. The work covered bacteriophages, microbial ecology and antimicrobial resistance. Univer

    NewsPhage BiologyAMR
  8. UpdatesSep 16, 2026

    Prophage-encoding engineered bacteria enable prophylactic lytic phage therapy for enteric infection in mice

    Engineered non-pathogenic E. coli producing lytic phages protected mice against Salmonella infection in a preclinical proof-of-concept study. Nature Microbiology

    UpdatesPapersPhage BiologyPhage Therapy
  9. JobsSep 16, 2026

    Postdoctoral researcher in microbiota and bacteriophage–immune interactions — University of Utah (Round Lab, Huntsman Cancer Institute)

    The University of Utah's Round Laboratory (Huntsman Cancer Institute, Salt Lake City) is recruiting a full-time postdoctoral research associate to lead an independent project in one of two directions: early-life microbiota–immune interactio

    JobsPhage BiologyPostdocMicrobiome
  10. NewsSep 3, 2026

    Yuping Li (University of Basel) wins €1.5M ERC Starting Grant on bacterial sensing of jumbophages

    Professor Yuping Li of the Biozentrum, University of Basel, has received a European Research Council Starting Grant, funded with 1.5 million euros over five years, to study how bacteria detect and defend themselves against jumbophages, gian

    NewsFundingPhage Biology
  11. JobsSep 1, 2026

    University at Buffalo postdoctoral associate — phage–Bacteroidales research

    Full-time Postdoctoral Associate in Dr. Yolanda Huang’s lab at the University at Buffalo. Potential projects include studying antimicrobial stress tolerance, carbon metabolic pathways and genetic determinants underlying bacteria-phage inter

    JobsPostdocPhage BiologyBioinformatics
  12. UpdatesAug 26, 2026

    Phage PAK_P3 genome folding and host chromosome rearrangement during Pseudomonas aeruginosa infection (Science Advances)

    Bignaud, Lamy-Besnier, Koszul, Debarbieux, Marbouty and colleagues followed the 3D organization of the virulent phage PAK_P3 genome during infection of Pseudomonas aeruginosa. The phage genome rapidly decondenses into a specific 3D organiza

    UpdatesPapersPhage BiologyPhage Genomics
  13. NewsAug 19, 2026

    EMBL researchers show phage T7 kinase phosphorylates much of the bacterial proteome to shut down host defences (Nature)

    EMBL Heidelberg researchers report in Nature that the kinase of phage T7 (T7K) causes almost every bacterial protein to be phosphorylated, at least in part of its pool, within minutes of infection, preferentially targeting DNA-binding prote

    NewsPhage Biology
  14. NewsJul 14, 2026

    Maryland-led study predicts variation in individual phage infections

    A model infers differences between individual phage infections from population-level measurements, checked against single-cell experiments in a marine phage–cyanobacterium system. University of Maryland — Jennifer Holland

    NewsPhage Biology
  15. JobsJul 1, 2026

    Postdoctoral Associate, Silveira Lab — University of Miami

    The Silveira Lab is searching for a Postdoctoral Associate to investigate how bacteriophages modulate geochemical biomarkers in green and purple sulfur bacteria. The NASA-funded project combines field experiments and bioinformatic analyses.

    JobsPhage BiologyPostdoc
  16. NewsJun 25, 2026

    Regulation of E. coli F defense systems during T5 infection

    Judith Sar discusses the regulation of E. coli F anti-phage defense genes during T5 infection in a Phages.fr talk hosted on Canal-U. Phages.fr on Canal-U

    NewsTalksMediaPhage Biology
  17. UpdatesJun 19, 2026

    The biology of jumbo phages (Nature Communications Review)

    A Nature Communications Review by Sam P. B. van Beljouw and Li Yuping (Biozentrum, University of Basel) on jumbo bacteriophages, whose double-stranded DNA genomes exceed 200 kb. It covers their diversity, evolutionary origins, distinctive m

    UpdatesPapersReviewPhage Biology
  18. UpdatesJun 18, 2026

    A meta-analysis of infant gut viromes reveals global patterns in bacteriophage community assembly and functional capacity over the first three years of life

    A meta-analysis of 12 infant cohorts across 8 countries (1,893 samples from 999 infants) models gut virome development over the first three years of life. Viral richness rose significantly over the first eight months alongside a loss of com

    UpdatesPapersMicrobiomePhage Biology
  19. UpdatesJun 12, 2026

    Bacteriophages hijack 2′,3′-cNMPs to enhance transposase-mediated phage DNA integration in Acinetobacter baumannii (Science Advances)

    Cui and colleagues report in Science Advances that Acinetobacter baumannii makes 2′,3′-cyclic nucleotide monophosphates (2′,3′-cNMPs) with the ribonuclease RnaA and senses them through the receptor protein CRPAb, which affects the interacti

    UpdatesPapersPhage Biology
  20. UpdatesJun 4, 2026

    Prevalent gut phages encode modular adhesins mediating epithelial binding and endoplasmic reticulum trafficking

    A high-throughput platform identified gut phages that adhere to epithelial layers and the immunoglobulin (Ig)-like domain proteins that mediate it: displayed on a non-adherent phage, they confer epithelial binding and internalization in vit

    UpdatesPapersMicrobiomePhage Biology
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