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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesMar 7, 2025

    Phage cocktail or personalized therapy — an age-old binary, or a spectrum after all? Minyoung Kevin Kim (Stanford University)

    Phage cocktail or personalized therapy — an age-old binary, or a spectrum after all? Minyoung Kevin Kim (Stanford University) and colleagues from Mayo Clinic, QAMH, & KU Leuven published a review on how phage therapy is currently being impl

    UpdatesPhage therapyMultidrug-resistant infectionsReview
  2. UpdatesMar 7, 2025

    M. Fernanda Vieira (University of Minho) and colleagues published a new paper on machine learning for phage depolymerase iden

    M. Fernanda Vieira (University of Minho) and colleagues published a new paper on machine learning for phage depolymerase identification, showing PhageDPO achieves 96% accuracy in predicting depolymerases with potential biotechnological appl

    UpdatesResearch paperMachine LearningPhage Depolymerase
  3. UpdatesMar 7, 2025

    Rebecca Tarnopol (University of California, Berkeley) and colleagues published a new paper on experimental horizontal gene tr

    Rebecca Tarnopol (University of California, Berkeley) and colleagues published a new paper on experimental horizontal gene transfer in Drosophila, showing that phage-derived genes confer innate immunity against parasitoid wasps when express

    UpdatesResearch paperDrosophilaGene transferImmunity
  4. UpdatesMar 7, 2025

    Antoine Culot (Rime Bioinformatics) and colleagues published a new paper on high-performance phage genome annotation, showing

    Antoine Culot (Rime Bioinformatics) and colleagues published a new paper on high-performance phage genome annotation, showing their automated rTOOLS pipeline provides functional annotations comparable to manual methods, enabling safer and f

    UpdatesResearch paperGenome Annotation
  5. UpdatesMar 7, 2025

    Andrea Kwa (Singapore General Hospital) and colleagues have announced Singapore’s second phage therapy case.

    Andrea Kwa (Singapore General Hospital) and colleagues have announced Singapore’s second phage therapy case.

    UpdatesPhage TherapyNewsSingapore
  6. UpdatesFeb 28, 2025

    Newbie with questions on phages: I am an absolute newbie to phages, but, I figured here would be a good place to ask. Anyone

    Newbie with questions on phages: I am an absolute newbie to phages, but, I figured here would be a good place to ask. Anyone know of any phages capable of targeting Candidatus Liberibacter Asiaticus? Anyone do any research with phages on th

    UpdatesCommunitySeeking phages for research
  7. UpdatesFeb 28, 2025

    The First Symposium of the Danish Viruses of Microbes Network will be hosted June 11-13, 2025 in Copenhagen. The meeting will

    The First Symposium of the Danish Viruses of Microbes Network will be hosted June 11-13, 2025 in Copenhagen. The meeting will showcase recent phage research and foster collaboration among Nordic scientists.

    UpdatesCommunitySymposiumViruses of Microbes
  8. UpdatesFeb 28, 2025

    The International Scientific Association for Probiotics and Prebiotics (ISAPP) is hosting a conference, taking place on June

    The International Scientific Association for Probiotics and Prebiotics (ISAPP) is hosting a conference, taking place on June 26-28, 2023 in Denver, Colorado, USA. The event aims to address scientific developments and challenges in probiotic

    UpdatesCommunityConference
  9. UpdatesFeb 28, 2025

    The European Bone and Joint Infection Society (EBJIS) is hosting a conference called EBJIS 2025: Advancing Bone & Joint Infec

    The European Bone and Joint Infection Society (EBJIS) is hosting a conference called EBJIS 2025: Advancing Bone & Joint Infection Management, taking place Sept 11-13, 2025 in Bologna, Italy.

    UpdatesCommunityConference
  10. UpdatesFeb 28, 2025

    The European Committee on Antimicrobial Susceptibility Testing (EUCAST) will host a Phage Susceptibility Testing Symposium Ma

    The European Committee on Antimicrobial Susceptibility Testing (EUCAST) will host a Phage Susceptibility Testing Symposium March 12 2025.

    UpdatesCommunityEUCASTAntimicrobial susceptibility testing
  11. UpdatesFeb 28, 2025

    Garyk Brixi (Arc Institute and Stanford University) and colleagues have expanded on Evo 1, which was trained on prokaryotic a

    Garyk Brixi (Arc Institute and Stanford University) and colleagues have expanded on Evo 1, which was trained on prokaryotic and phage genomes, to create Evo 2, now the largest AI model in biology. It was trained on 9.3 trillion nucleotides

    UpdatesGenomicsAI and biologyPreprint
  12. UpdatesFeb 28, 2025

    Benjamin Adler (University of California, Berkeley) and colleagues published CRISPRi-ART for phage functional genomics, a new

    Benjamin Adler (University of California, Berkeley) and colleagues published CRISPRi-ART for phage functional genomics, a new broad-spectrum phage functional genomics platform. It leverages RNA-targeting dCas13d to selectively interfere wit

    UpdatesResearch paperCRISPRi-ART
  13. UpdatesFeb 28, 2025

    Melissa Cammuso (The Ottawa Hospital) and colleagues have published a preprint in medRxiv on the first use of phage therapy i

    Melissa Cammuso (The Ottawa Hospital) and colleagues have published a preprint in medRxiv on the first use of phage therapy in Canada for life-threatening, MDR Staphylococcus epidermidis periprosthetic joint infection. This ‘n of 1 trial’ d

    UpdatesPreprintCase reportPhage therapy
  14. UpdatesFeb 28, 2025

    Los Angeles Biotech startup Parallel Health has announced an expanded protocol for personalized skin treatments using microbi

    Los Angeles Biotech startup Parallel Health has announced an expanded protocol for personalized skin treatments using microbiome science and phage therapy. Their approach combines microbiome testing, custom phage serums, telehealth, and pre

    UpdatesPhage therapyMicrobiomePress release
  15. UpdatesFeb 28, 2025

    Maria Touceda-Suarez (University of Arizona) and colleagues compiled a report on last year’s successful International Soil Vi

    Maria Touceda-Suarez (University of Arizona) and colleagues compiled a report on last year’s successful International Soil Virus Conference 2024, showing key developments in soil viral ecology and recommendations for future research in this

    UpdatesConference reportSoil viruses
  16. UpdatesFeb 25, 2025

    Coating phage-infected bacteria with polymer preserves phage vitality and improves oral phage therapy in mice (Nature Biomedical Engineering)

    Wrapping individual phage-infected bacteria in a polymeric nanoscale coating preserves the vitality of the phages released on lysis, which otherwise have severely degraded tail proteins. In mice with bacterially induced enteritis and associ

    UpdatesPapersPhage TherapyPhage Engineering
  17. UpdatesFeb 21, 2025

    From Lars Hestbjerg Hansen via LinkedIn: Hi all. I'm looking for E. coli isolates. Hundreds of them! Even thousands! Preferab

    From Lars Hestbjerg Hansen via LinkedIn: Hi all. I'm looking for E. coli isolates. Hundreds of them! Even thousands! Preferably, non-clinical isolates. Please contact me if you have a large DIVERSE collection or if you know someone who has.

    UpdatesCommunitySeeking phages for research
  18. UpdatesFeb 21, 2025

    Ruby Lin and colleagues have created an innovative virtual reality education platform for phage therapy patients. The VR expe

    Ruby Lin and colleagues have created an innovative virtual reality education platform for phage therapy patients. The VR experience guides patients through the entire phage therapy journey, from lab testing to bedside treatment, aiming to r

    UpdatesCommunityEducationVRPhage therapy
  19. UpdatesFeb 21, 2025

    José R Penadés (Imperial College London) and colleagues have shown that a new AI tool, ‘AI co-scientist’ (built by Google), w

    José R Penadés (Imperial College London) and colleagues have shown that a new AI tool, ‘AI co-scientist’ (built by Google), was able to accurately predict their (unpublished) experimental findings about how phage-inducible chromosomal islan

    UpdatesAI toolsPICI
  20. UpdatesFeb 21, 2025

    Proteon Pharmaceuticals has announced the registration of its Salmonella phage-based chicken feed product, BAFASAL PRO, in Br

    Proteon Pharmaceuticals has announced the registration of its Salmonella phage-based chicken feed product, BAFASAL PRO, in Brazil! This is Proteon’s third product approval in Brazil, and second in the last year!

    UpdatesBiotech NewsRegulatory approval
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