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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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231 news items

  • Tulane Ventures invests $250,000 in Biophoundry to advance engineered phage therapies

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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesJun 2, 2023

    A new phage therapy company has launched! Phiogen is a spinoff from Baylor College of Medicine, located at Texas Medical Cent

    A new phage therapy company has launched! Phiogen is a spinoff from Baylor College of Medicine, located at Texas Medical Center's Innovation Hub. Based on TAILOR Labs’ phage therapy work, and building on patented technology for evolving pha

    UpdatesBiotech newsPhage therapy
  2. UpdatesJun 2, 2023

    Fixed Phage has shown that their technology, which stably immobilizes phages to excipients, can efficiently treat acne when i

    Fixed Phage has shown that their technology, which stably immobilizes phages to excipients, can efficiently treat acne when immobilized onto nylon beads and delivered through a cream, reducing the bacterial load on the skin.

    UpdatesBiotech newsAcnePhage therapy
  3. NewsMay 31, 2023

    SNIPR Biome reports positive interim Phase 1 results for CRISPR-armed phage SNIPR001

    SNIPR Biome announced positive interim results from its Phase 1 trial of SNIPR001, a cocktail of four CRISPR-armed phages that targets E. coli, including antibiotic-resistant strains, in the gut. In 36 healthy volunteers (24 on three dose l

    NewsClinical TrialsPhage Therapy
  4. UpdatesMay 26, 2023

    Phage utility against Burkholderia cepacia complex species has been restricted by the prevailing paradigm of only using rare,

    Phage utility against Burkholderia cepacia complex species has been restricted by the prevailing paradigm of only using rare, obligately lytic phages, due to the perception that lysogenic phages are therapeutically unsuitable. Philip Lauman

    UpdatesResearch paperLysogenyPhage therapy
  5. UpdatesMay 26, 2023

    Aleksandra Petrovic Fabijan and colleagues have written a perspective piece on translating phage therapy into the clinic. The

    Aleksandra Petrovic Fabijan and colleagues have written a perspective piece on translating phage therapy into the clinic. They delve into the history, turning points, recent studies and successes, and dig into the remaining biological, regu

    UpdatesClinical studiesReviewPhage therapy
  6. NewsMay 24, 2023

    Adaptive Phage Therapeutics announces collaboration and license agreement with IPTC

    Adaptive Phage Therapeutics announces a collaboration and license agreement with the Israeli Phage Therapy Center at Hebrew University and Hadassah Medical Center. The agreement grants APT exclusive rights to make, use and sell licensed pha

    NewsPhage Therapy
  7. JobsMay 19, 2023

    The Deng lab at the Technical University of Munich is seeking a PhD student to investigate novel therapeutics for preterm inf

    The Deng lab at the Technical University of Munich is seeking a PhD student to investigate novel therapeutics for preterm infant infections. The team will focus on gut colonisation by pioneer bacterial species and its interruption in preter

    JobsGut microbiomePhD projectPreterm infantsPhage therapy
  8. UpdatesMay 19, 2023

    Oluwasegun Daramola of the Ibadan Bacteriophage Research Team was interviewed an episode of the Medlab LabCast called Phage T

    Oluwasegun Daramola of the Ibadan Bacteriophage Research Team was interviewed an episode of the Medlab LabCast called Phage Therapy: The Enemy of My Enemy Is My Friend.

    UpdatesCommunityPhage therapyPodcast
  9. UpdatesMay 19, 2023

    Tune in to Science Friday for an interview with Graham Hatfull about phage therapy: “Are Phages a new page in medicine?”

    Tune in to Science Friday for an interview with Graham Hatfull about phage therapy: “Are Phages a new page in medicine?”

    UpdatesCommunityPhage therapyPodcast
  10. UpdatesMay 19, 2023

    Jagdev Singh and colleagues published a clinical trial announcement that will involve a single-arm, open-labelled study inves

    Jagdev Singh and colleagues published a clinical trial announcement that will involve a single-arm, open-labelled study investigating the safety and tolerability of intrabronchial and nebulized phage treatment in children with cystic fibros

    UpdatesClinical TrialCystic fibrosisPhage therapy
  11. UpdatesMay 19, 2023

    Copenhagen-based SNIPR Biome, a CARB-X portfolio company, has developed SNIPR001, a cocktail of CRISPR-armed phages designed

    Copenhagen-based SNIPR Biome, a CARB-X portfolio company, has developed SNIPR001, a cocktail of CRISPR-armed phages designed to target E. coli. A recent release by Robin Berghaus of CARB-X highlights the potential of SNIPR001 to prevent blo

    UpdatesBiotech newsClinical TrialPhage therapyPhages and cancer
  12. UpdatesMay 18, 2023

    UK public attitudes to phage therapy: survey of 787 people

    PLOS ONE survey (N = 787, Prolific) of UK public awareness and acceptance of phage therapy found moderate acceptance, a mean likelihood of 4.71 on a 1-7 scale. Priming participants to think about novel medicines and antibiotic resistance ra

    UpdatesPapersPhage Therapy
  13. UpdatesMay 12, 2023

    “Resistant bacteria do a lot of taking…” The Center for Disease Control published Diane Shader Smith’s story of her daughter

    “Resistant bacteria do a lot of taking…” The Center for Disease Control published Diane Shader Smith’s story of her daughter Mallory’s battle against a superbug, how phage therapy could have saved her life, and why more people need to share

    UpdatesAMRPhage therapy
  14. UpdatesMay 5, 2023

    The Phage Therapy Today podcast interviewed Johan Wikstroem, the CEO of tolka.ai, about his story in transitioning from tech

    The Phage Therapy Today podcast interviewed Johan Wikstroem, the CEO of tolka.ai, about his story in transitioning from tech to biotech and founding a phage therapy company with the goal of treating his own M. abscessus infection and helpin

    UpdatesCommunityPhage therapyPodcast
  15. UpdatesMay 5, 2023

    Kids Research (part of Sydney Children's Hospitals Network) is hosting a webinar on May 19, 2023 at 2:00 PM AEST on phage the

    Kids Research (part of Sydney Children's Hospitals Network) is hosting a webinar on May 19, 2023 at 2:00 PM AEST on phage therapy entitled "Phage Therapy in Australia: STAMPing out problematic infections". The webinar will be presented by P

    UpdatesCommunityClinical TrialWebinarPhage therapy
  16. UpdatesMay 5, 2023

    From Sabrina Green via Twitter: Check out this documentary on #phage therapy in Belgium and Portugal. It is in Portuguese but

    From Sabrina Green via Twitter: Check out this documentary on #phage therapy in Belgium and Portugal. It is in Portuguese but interviews mostly in English.

    UpdatesCommunityDocumentaryPhage therapy
  17. UpdatesMay 5, 2023

    Toronto clinician Dr. Greg German: reports the first research use of a phage cocktail to treat an infection in Canada!

    Toronto clinician Dr. Greg German: reports the first research use of a phage cocktail to treat an infection in Canada!

    UpdatesMilestonePhage therapy
  18. UpdatesMay 5, 2023

    Y. Emre Gencay and colleagues have developed engineered phages with CRISPR-Cas machinery to reduce E. coli in mice. The phage

    Y. Emre Gencay and colleagues have developed engineered phages with CRISPR-Cas machinery to reduce E. coli in mice. The phages, called SNIPR001, were well tolerated in mouse models and minipigs, and out-competed their ancestral wild-type ph

    UpdatesCRISPRPhage therapy
  19. UpdatesMay 4, 2023

    Engineered phage with antibacterial CRISPR–Cas selectively reduce E. coli burden in mice

    Nature Biotechnology paper on SNIPR001: from a library of 162 wild-type phages, eight with broad E. coli coverage were selected and engineered with tail fibers and CRISPR–Cas machinery to target E. coli. A combination of the four most compl

    UpdatesPapersPhage EngineeringPhage Therapy
  20. UpdatesApr 28, 2023

    The Israeli Phage Therapy Center (IPTC) has received 159 requests for phage therapy, with 38% of them being for multi-drug re

    The Israeli Phage Therapy Center (IPTC) has received 159 requests for phage therapy, with 38% of them being for multi-drug resistant bacteria. Respiratory and bone infections were the most prevalent indications. 20 phage therapy courses wer

    UpdatesCompassionate usePhage therapy
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