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Here’s a handy comparison of expression systems for phage lysin production, with key considerations for host selection and evaluating recent literature.

A new first in human phase 1 randomized, double-blind trial of Intralytix's ShigActive™, a Shigella phage preparation, shows it is safe and well tolerated when orally administered.

Guadalupe Valencia-Toxqui and Jolene Ramsey (Texas A&M University) published a new phage classification guide, orienting newcomers to four common ways phages are currently classified: infection cycle, morphology, taxonomy, and supergroup. B

Nicolas Kieffer (Universidad Complutense de Madrid) and colleagues published a new preprint on identification of phage defense systems encoded by mobile integrons, showing that integrons can encode phage defense systems, including Lamassu,

Max Wilkinson (Massachusetts Institute of Technology) and colleagues have described how phage-triggered reverse transcription assembles a toxic repetitive gene from a noncoding RNA, showing a new mode of genetic regulation in prokaryotes.

Rabia Fatima (McMaster University) and colleagues published a new paper on temperate phage-antibiotic synergy in P. aeruginosa, showing widespread synergy between temperate phages and antibiotics, but varying by phage, host, and antibiotic

Eleonora Turrini, Luca Ulfo (University of Bologna) and colleagues published a new paper on molecular engineering of an M13 phage nanovector for photodynamic treatment of colon cancer cells. They show effective colorectal cancer cell targe

Congratulations to Simon Roux for winning the 2025 ASM Microbiome Data Prize for his outstanding contributions to microbiome research!

The Phage Hunters Training and Research Program (PHTRP) has launched a fundraiser to support their Phage Training Startup Fund. This initiative aims to equip young scientists in Africa and other developing countries with the skills needed

The ISVM (International Society for Viruses of Microbes is launching a logo design competition to create a new visual identity for the society, with submissions due by October 6th via the ISVM Board's email.

The Veterinary Biologicals Committee of the International Alliance for Biological Standardization will host a workshop on the quality, safety, and efficacy of phages for veterinary use on September 5, 2024, to discuss strategies for reducin

Only a few more days to vote for the International Society for Viruses of Microbes Executive Board candidates! (Ends Oct 21) ISVM members are invited to participate in the upcoming elections for the ISVM Executive Board to shape the future

Only a few more days to vote for the International Society for Viruses of Microbes Executive Board candidates! (Ends Oct 21) ISVM members are invited to participate in the upcoming elections for the ISVM Executive Board to shape the future

Nicholas Smith (University at Buffalo) and Dwayne Roach (San Diego State University) received a $3.6 million NIH grant to study pharmacokinetics and pharmacodynamics of mechanistically aware phage cocktails.

Associate Professor Jeremy Barr (Monash University) received $500,000 USD from the Bill & Melinda Gates Foundation to investigate how phages interact with the human immune system and their potential implications for treating inflammatory di

Phage protein moonlighting alert! Abdulrazak Alsaleh (Liverpool John Moores University) and colleagues published a new paper on how large serine integrases utilize scavenged phage proteins to control the directionality of integration.

Amit Rimon (Hebrew University of Jerusalem) and colleagues published a new paper on combinatorial treatment of pulsed blue light and phage therapy for antibiotic-resistant P. aeruginosa, showing a synergistic bactericidal effect on plankton

Matt McEnany (U Colorado) and Kevin Outterson (Boston University, Founder and Executive Director of CARB-X) published a new paper on evaluating Germany's new antimicrobial reimbursement reforms. They compare these reforms to delinked pull i

David Pride, Douglas Conrad (UC San Diego) and Daria Van Tyne (University of Pittsburgh) received a $1,487,500 research grant from Emily's Entourage, a CF nonprofit to launch a phage clinical trial for combatting CF infections.

Cytophage Technologies (Winnipeg, Canada) has announced a launch of ready-to-use lyophilized phage tablets for poultry.