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In a recent perspective piece, Christine Szymanski (University of Georgia) highlights the limitless resources for exploitation that phages provide. She discusses their use in various fields such as phage therapy, gene transduction, and glyc

The Centre for Phage Research at the University of Leicester, UK is celebrating its one-year anniversary! Martha Clokie and Andrew Millard reflect on the first year.

A retrospective observational analysis of the first 100 consecutive cases of personalized phage therapy facilitated by a Belgian consortium in 35 hospitals across 12 countries (2008-2022) reports clinical improvement in 77.2% and eradicatio

Registration is now open for the 2024 International Soil Virus Conference! Soil virologists and enthusiasts will gather to explore the multifaceted roles of soil viruses within a One Health framework, with a special focus on meta-omics cha

Meow! A cat named Squeaks needed phage therapy after falling 3 stories, and thanks to Ronen Hazan’s lab in Jerusalem, she got it, and it saved her leg!

Stephen Tang (Columbia University, USA) and colleagues published a new preprint on de novo gene synthesis by an antiviral reverse transcriptase. They demonstrate bacterial creation of extrachromosomal genes via rolling-circle reverse transc

Toomas Mets (Lund University, Sweden) and colleagues published a new paper on the mechanism of phage sensing and restriction by toxin-antitoxin-chaperone systems. They show how E. coli TAC systems detect and neutralize phages by targeting m

Toshiki Nagakubo (University of Tsukuba, Japan) and colleagues published a new paper on how contractile injection systems promote Streptomyces spore formation via a phage tapemeasure-related protein.

Phages spotted on the big screen! "The Good Doctor" TV series finale apparently involves treatment of an important character with phage therapy!

Registration is now open for the 2024 International Soil Virus Conference! Soil virologists and enthusiasts will gather to explore the multifaceted roles of soil viruses within a One Health framework, with a special focus on meta-omics cha

Dimi Boeckaerts and colleagues have developed a new AI model, PhageHostLearn, which predicts Klebsiella phage-host interactions at the strain level, and in a ‘ranking format’ that is directly actionable in the lab. Paper | Behind-the-paper

Cristina Howard-Varona (Ohio State University) and colleagues used a systems biology approach to show how virocells (virus-infected cells) reprogram their metabolism according to different nutrient conditions like low phosphate, and how the

Svenja Thöneböhn (Justus-Liebig-Universität Gießen, Germany) and colleagues have identified new components of the Shewanella phage LambdaSo lysis system, including a pinholin/signal-anchor-release (SAR) endolysin system and a two-component

M. J. N. Thomas (University of Manchester) and colleagues published a new paper in mSystems called ‘What makes a temperate phage an effective bacterial weapon?’. They combine mathematical models and experimental work to reveal how temperate

Niels Vander Elst (Karolinska Institute, Sweden) has reviewed the potential of phage-derived endolysins against bovine mastitis caused by streptococci and staphylococci, highlighting recent progress in engineering endolysins for robust acti

ASM Microbe 2024 (June 13-17 in Atlanta, Georgia) is hosting a session called Phage Therapy in the Age of AMR: Strategies to Accelerate Phage Therapy from Lab to Market this year! Hear from Ashlan Kunz Coyne, Susan Lehman, Ghady Haidar, Kev

Wilfried Moreira (Singapore Centre for Environmental Life Sciences Engineering) invites submissions to a Special Issue of the International Journal of Molecular Sciences entitled "Bacteriophage Biology and Bacteriophage-Derived Technologies

The Phage Bioinformatics Wish List Survey is live! (Thanks to the 31 respondents to date! The data is shaping up to be super informative!) This survey aims to better understand the needs and satisfaction levels of phage biologists regardi

Dr Ameneh Khatami (University of Sydney, Phage Australia) has been awarded $4.3 million to investigate the use of a locally produced two-phage combination that targets S. aureus to see if it provides an advantage in addition to antibiotics

Marie Attwood (University of Leicester) and colleagues published a new preprint on the development of antibacterial drug-plus-phage combination assays. They demonstrate that microbroth methodologies based on ISO 2776 and time-kill curves ca