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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesJul 21, 2023

    The Ohio State University and IPATH were awarded $175k from the Herbert W. Hoover Foundation to address AMR through phage the

    The Ohio State University and IPATH were awarded $175k from the Herbert W. Hoover Foundation to address AMR through phage therapy, with students in OSU’s Science Education Alliance-LAB undergraduate program isolating and characterizing phag

    UpdatesGrant fundingPhage TherapyAntimicrobial ResistanceUndergraduate
  2. UpdatesJul 21, 2023

    A new preprint by Martin Plymouth, Stephanie Lynch and colleagues investigates the attitudes of Australian infectious disease

    A new preprint by Martin Plymouth, Stephanie Lynch and colleagues investigates the attitudes of Australian infectious diseases physicians towards phage therapy.

    UpdatesPhage TherapyInfectious Diseases PhysiciansSurveyPreprint
  3. UpdatesJul 21, 2023

    Phynteny, a synteny-based annotation tool for phage genes, has been developed by @susiegriggo_ to assign hypothetical phage p

    Phynteny, a synteny-based annotation tool for phage genes, has been developed by @susiegriggo_ to assign hypothetical phage proteins to a PHROG category based on gene order conservation.

    UpdatesBioinformatics tools
  4. UpdatesJul 21, 2023

    Phage researchers can now access PhageBox, an open-source digital microfluidic extension that integrates temperature and elec

    Phage researchers can now access PhageBox, an open-source digital microfluidic extension that integrates temperature and electromagnetic modules, which can be used for phage research, as recently demonstrated by Dreycey Albin (University of

    UpdatesResearch paperOpen source toolHardware
  5. UpdatesJul 20, 2023

    Engineered reporter phages detect E. coli, Enterococcus and Klebsiella in urine within 5 hours

    ETH Zurich researchers genetically engineered two virulent phages per uropathogen (E. coli, Enterococcus spp., Klebsiella spp.) to express a nanoluciferase reporter on infection and tested the bioluminescence assay on 206 patient urine samp

    UpdatesPapersDiagnosticsPhage Engineering
  6. UpdatesJul 14, 2023

    Are you a phage enthusiast looking to isolate your own phage? Check out this beginner-friendly guide by Raphael Hans Lwesya f

    Are you a phage enthusiast looking to isolate your own phage? Check out this beginner-friendly guide by Raphael Hans Lwesya for tips and tricks!

    UpdatesCommunityPhage isolationGuide
  7. UpdatesJul 14, 2023

    The Phage Australia team at the Westmead Institute for Medical Research has been awarded $3.5 million by the NSW Government t

    The Phage Australia team at the Westmead Institute for Medical Research has been awarded $3.5 million by the NSW Government to address the phage manufacturing bottleneck for phage therapy patients.

    UpdatesPhage TherapyFunding news
  8. UpdatesJul 14, 2023

    NHS Tayside's orthopaedic department has successfully treated a joint infection using phage therapy, the first time phage the

    NHS Tayside's orthopaedic department has successfully treated a joint infection using phage therapy, the first time phage therapy has been used in the UK to treat a bone/joint infection.

    UpdatesPhage TherapyJoint Infection
  9. UpdatesJul 14, 2023

    Tejas Dharmaraj (Stanford University School of Medicine) and colleagues describe the use of dynamic light scattering to measu

    Tejas Dharmaraj (Stanford University School of Medicine) and colleagues describe the use of dynamic light scattering to measure changes in phage physical state, finding that phages tend to decay and form aggregates, and that degree of aggre

    UpdatesPreprintDynamic Light ScatteringPhage stability
  10. UpdatesJul 14, 2023

    Thilo Köhler (Geneva University Hospitals) and colleagues report successful treatment of a 41-year-old patient with a P. aeru

    Thilo Köhler (Geneva University Hospitals) and colleagues report successful treatment of a 41-year-old patient with a P. aeruginosa infection using aerosolized phage therapy. They followed evolution of phage and bacteria in respiratory samp

    UpdatesPhage therapyResearch paperTherapeutic monitoring
  11. UpdatesJul 14, 2023

    Meghan Rose McGillin (Cornell University) has written a post on key insights from ASM Microbe 2023, with a focus on how much

    Meghan Rose McGillin (Cornell University) has written a post on key insights from ASM Microbe 2023, with a focus on how much phage work was presented. She highlights new developments in phage therapy, including breakthroughs targeting B. ce

    UpdatesConference reportPhage therapy
  12. UpdatesJul 7, 2023

    Greg German and his team in Toronto have successfully used personalized phage therapy to cure a UTI in a patient, as covered

    Greg German and his team in Toronto have successfully used personalized phage therapy to cure a UTI in a patient, as covered by Canada’s CTV News. This is the first patient in their clinical trial, and constitutes Canada’s first phage thera

    UpdatesClinical trialPhage therapy
  13. UpdatesJul 7, 2023

    Matthias Fischer (Max Planck Institute for Medical Research) and colleagues have discovered a stunning structural diversity o

    Matthias Fischer (Max Planck Institute for Medical Research) and colleagues have discovered a stunning structural diversity of giant virus-like particles in forest soil, including giant icosahedral capsids with structural modifications not

    UpdatesSoilPhage diversityStructural biologyPreprint
  14. UpdatesJul 7, 2023

    Krista Freeman (University of Pittsburgh) and colleagues have found that several mycobacteriophages have O-linked glycans, me

    Krista Freeman (University of Pittsburgh) and colleagues have found that several mycobacteriophages have O-linked glycans, mediated by phage-encoded glycosyltransferases, which can alter antibody binding and recognition.

    UpdatesGlycosylationMycobacteriophages
  15. UpdatesJul 7, 2023

    Designer phages by Eligo Bioscience have been highlighted by the World Economic Forum as a key transformative force for the c

    Designer phages by Eligo Bioscience have been highlighted by the World Economic Forum as a key transformative force for the coming years, coincidentally on World Microbiome Day.

    UpdatesDesigner PhagesWorld Economic ForumMicrobiome
  16. UpdatesJul 7, 2023

    Phage therapy was covered in ‘Grow by Ginkgo’ magazine’s Scale issue; well-researched piece with a great narrative! Good one

    Phage therapy was covered in ‘Grow by Ginkgo’ magazine’s Scale issue; well-researched piece with a great narrative! Good one to share with public audiences, and highlights that the synthetic biology / biomanufacturing community is starting

    UpdatesPhage TherapyMagazine
  17. UpdatesJul 5, 2023

    This week the PhageCast podcast interviewed Rob Lavigne about his phage work, including P. aeruginosa phage dark matter, the

    This week the PhageCast podcast interviewed Rob Lavigne about his phage work, including P. aeruginosa phage dark matter, the Igy peptide, and the significance of RNA sequencing.

    UpdatesCommunityPodcastPhage dark matterInterview
  18. UpdatesJul 5, 2023

    BSVoM Symposium, Belgium is hosting a phage research symposum on September 8, 2023 in Liège (Belgium). Topics will cover: fun

    BSVoM Symposium, Belgium is hosting a phage research symposum on September 8, 2023 in Liège (Belgium). Topics will cover: fundamental research in phage ecology, fundamental research in phage biology, and present and future applications of p

    UpdatesCommunitySymposiumPhage research
  19. UpdatesJul 5, 2023

    PhageEurope (Phage EU) is a new coalition of likeminded stakeholders who represent phages in industry, the scientific communi

    PhageEurope (Phage EU) is a new coalition of likeminded stakeholders who represent phages in industry, the scientific community and civil society who wants to realize the full potential of phages in Europe. They are holding a webinar 11 Jul

    UpdatesCommunityWebinarPhage therapyRegulation
  20. UpdatesJul 5, 2023

    Life Science Network, Denmark interviewed Dr. Michela Gambino about her career from culture and natural heritage conservation

    Life Science Network, Denmark interviewed Dr. Michela Gambino about her career from culture and natural heritage conservation to phage microbiology.

    UpdatesCommunityConservationCultural HeritageInterviewCareer
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