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Per Kristian Thorén Edvardsen (Norwegian University of Life Sciences) and colleagues published a new paper on a cryptic prophage endolysin with muramidase activity. They solve its crystal structure and show 10,000-fold higher activity than

Seyoung Ko (Ulsan National Institute of Science and Technology, Korea) and colleagues published a new paper on deep learning-guided structural analysis of phage KPP105. Structural similarity analysis showed how its receptor binding protein

Jason Wilson (University of Sheffield) and colleagues published a new paper on structural analysis of a phage that penetrates bacterial S-layers, showing the phage has an unusually long tail that contracts less than other phages, likely ena

Tong Zhang (Massachusetts Institute of Technology) and colleagues discovered a bacterial immunity protein that senses two unrelated phage proteins, showing that CapRelSJ46 in E. coli can directly bind two structurally different phage protei

Stephano Iglesias (Thomas Jefferson University, Philadelphia) and colleagues created a high-resolution structural atlas of Pseudomonas phage Pa193 using bioinformatics, proteomics, and cryogenic electron microscopy single particle analysis.

The Luque Lab at the University of Miami is hiring a postdoc to contribute to an innovative project combining structural virology, multi-scale modeling, and environmental virology.

Jun-Tao Zhang (Southern University of Science and Technology, China) colleagues have shown the structural basis for phage-mediated activation and repression of the anti-phage defense system DSR2. They use cryoEM to show how DSR2 interacts w

For 6 decades, it has been a mystery how ssDNA phages use their ‘maturation’ (Mat) protein (1 of 4 proteins encoded by the phage, known to be involved in plus recognition) to enter the host cell. Jirapat Thongchol (Texas A&M University) and

The Villa lab at UCSD is hiring two Research Technicians to help understand structural dynamics and macromolecular interactions (including phage-host interactions) at high resolution.

Barbara Maciejewska (University of Wrocław, Poland) and colleagues elucidated the structure and function of the capsular depolymerase KP34gp57 from Klebsiella phage KP34, describing for the first time monomeric phage depolymerases (’mini-de

University of Exeter is hiring a PhD researcher to employ high-resolution cryoEM imaging to achieve atomic-level structural characterisation of Burkholderia phages and study their adaptations to evade clearance by the innate immune system i

Matthias Fischer (Max Planck Institute for Medical Research) and colleagues have discovered a stunning structural diversity of giant virus-like particles in forest soil, including giant icosahedral capsids with structural modifications not

FAPESP - São Paulo Research Foundation, Brazil is hiring a post-doc to study the structure of different type IV pilus and their interactions with phages.

FAPESP - São Paulo Research Foundation, Brazil is hiring a post-doc to study the structure of different type IV pilus and their interactions with phages.

This week's EMDB (Electron Microscopy Data Bank) release includes this beautiful 4.4 Å single particle CryoEM structure of a phicrAss001 virion!

The University of Connecticut seeks to fill a non-tenure track Research and Teaching Scholar position (Assistant Research Professor) beginning in August 2023 who is interested in studying biochemical and biophysical aspects of dsDNA virus a

A subset of jumbo phages have recently been shown to encode a 'phage nucleus' for sequestering the phage genome away from host nucleolytic attack. Eliza Nieweglowska (University of California, San Francisco) and colleagues published a new p

In a new paper in Cell, Brianna Duncan-Lowey (Harvard Medical School) and colleagues determined the cryo-EM structures of the RADAR defense complex, revealing RdrA as a heptameric, two-layered AAA+ ATPase and RdrB as a dodecameric, hollow c

The Gao Lab at Stanford University is seeking a postdoctoral scientist in structural biology to join their new research team. The lab is focused on exploring and harnessing the vast diversity of genes throughout Earth’s microbiome to unders

Hawkins et al. published a new paper which provides the first complete structural analysis of the S. epidermidis–infecting phage Andhra. Key findings include elucidating critical features for virion assembly, host recognition, and penetrati