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Daniela Rothschild-Rodriguez (University of Southampton) and colleagues published a new paper on a community-driven Klebsiella phage resource, showing KlebPhaCol comprises 53 phages spanning 5 families, including a novel gut-associated orde

Tongqing Wei (Fudan University) and colleagues published a new paper on predicting phage-bacteria interactions using deep learning, showing DeepPBI-KG can accurately predict interactions based on key genes and outperforms existing methods o

Yuxing Wu (Guangxi University) and colleagues published a new paper on oral bacteriophage therapy for C. perfringens infections in piglets, showing phage vB_CpeP_15N3 could effectively prevent and treat C. perfringens type C infections in n

Marzanna Lusiak-Szelachowska (Hirszfeld Institute of Immunology and Experimental Therapy) and colleagues published a new paper on antiphage antibodies in phage therapy patients, showing antibodies appear late in treatment, particularly with

Minyoung Kevin Kim (Stanford University) and colleagues published a new paper on designing effective phage-antibiotic cocktails against bacterial infections, showing that combining phages from different "complementarity groups" targeting di

Saar Van Overfelt (Ghent University, Belgium) and colleagues published a new paper on quantifying bacteriophages using qPCR and double agar overlay (DAO) methods, showing DNase treatment reduces discrepancies between qPCR and DAO quantifica

Mahshid Khazani Asforooshan (Alzahra University, Iran) and colleagues have isolated and characterized a novel phage targeting Enterococcus faecium from hospital sewage. They designed a hydrogel-based drug delivery carrier, and showed the ph

Yangjing Xiong (Shanghai Jiao Tong University) and colleagues published a new paper on phage therapy for ETEC-induced diarrhea, showing phage JE01 reduced ETEC colonization and inflammation in mice, with fluorescent imaging revealing rapid

Hany Ahmed (Tanta University, Egypt) and colleagues published a new paper on isolation and characterization of a lytic phage against carbapenem-resistant A. baumannii (CRAB), showing the phage was effective in treating CRAB lung infections

Arturo Carabias (University of Copenhagen) and colleagues published a new paper on phage-encoded NAD restoration pathways, showing how phages counter bacterial immunity through innovative strategies to replenish NAD, providing insights for

Make the right ones glow! Eleanor Rand (Harvard Medical School) and colleagues developed a new targeted Phage Discovery method based on using multiple fluorescent markers, allowing for co-culture with multiple hosts and visualization of pha

Phages in sponges! A new study by Leon Steiner (GEOMAR Helmholtz Centre for Ocean Research, Kiel) and colleagues shows single-phage disturbances in the microbiome of marine sponges can disrupt microbial balance, enabling opportunistic bacte

Atif Khan (Bhabha Atomic Research Centre) and colleagues published a new paper showing chlorine-tolerant phages can inhibit growth and biofilm formation of chlorine-resistant K. pneumoniae isolated from a cooling water system.

Eric Nguyen (Stanford University, Arc Institute) and colleagues published a paper on their new machine learning model, Evo, a new generative AI model trained on millions of phage and bacterial genomes for designing new biological sequences

Baptiste Gaborieau (Université Paris Cité, France) and colleagues created a new machine learning model able to predict Escherichia phage-host interactions and design effective phage cocktails using only genomic data.

Léa Ibarlosa (CNRS-Université de Bordeaux, France) and colleagues published a new paper on amyloid signaling in antiphage defense, showing that amyloid proteins Bab and Agp form a novel E. coli antiphage system activating cell death upon in

Joaquín Martínez Martínez (Bigelow Laboratory for Ocean Sciences, Maine) and colleagues published a new paper on viral carbon and nitrogen assimilation by microbes, showing protists and bacteria can obtain significant carbon and nitrogen fr

Marwan Mahmood Saleh (University of Anbar, Iraq) and colleagues evaluated the lytic efficiency of a three-phage cocktail against multidrug-resistant P. aeruginosa isolates in vitro. The cocktail showed broad activity, including against XDR

Baptiste Gaborieau (Université Paris Cité, France) and colleagues published a new paper showing accurate prediction of strain-level phage-bacteria interactions in E. coli using only genomic data.

Dong Li (Beijing University of Chemical Technology) and colleagues published a new paper on how phage proteins can sequester signaling molecules from TIR and cGAS-like antiviral defense enzymes. Also check out this explainer thread by coau