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Researchers at Universitat Pompeu Fabra analysed the methylomes of six Cutibacterium acnes strains and showed that the killing specificity of phage PAD20 increases when its DNA acquires methylation from a methylation-competent strain. Phage

This review surveys computational tools that characterize uncultivated phage genomes from metagenomic sequence data, following the growth in phage genome discovery across diverse biomes. PubMed Central

Study in ACS Chemical Biology designing structure-guided mutants of bacteriophage Qβ (mQβ) as carriers for conjugate vaccines. Conjugated to tumour-associated carbohydrate antigens, mQβ elicited strong anti-TACA IgG with lower anti-carrier

INPHARED is an automated retrieval and analysis system for complete phage genomes and associated metadata. Its January 2021 collection contained 14,244 genomes; 75% were isolated on only 30 bacterial genera. PubMed Central

This teaching module uses PHASTER and other freely available tools for phage genome identification and phylogenetic analysis in undergraduate microbiology courses. The exercises were field-tested in classes and undergraduate directed resear

“What the Phage” combines bacteriophage identification tools with downstream annotation and classification in a parallel Nextflow workflow. It scales to thousands of datasets and helps users assess cases where tools disagree. bioRxiv

The 2020 PhageAI preprint describes a genome-sequence classifier for lytic and lysogenic life cycles. It reports 98.90% validation accuracy and 97.18% average test accuracy, and describes access through a REST service and Python package. Ph

A 2020 paper in PHAGE evaluates methods for processing sputum from patients with cystic fibrosis to detect Pf bacteriophage virion-derived nucleic acid, testing the effect of bead beating, DNase digestion and heating steps and quantifying P

An observational, open-label study assessed adjunctive intravenous AB-SA01 phage therapy in 13 critically ill patients with severe Staphylococcus aureus bacteraemia, including six with endocarditis, alongside standard medical and surgical c

Review in Cell Host & Microbe by Kortright, Chan, Koff and Turner (Yale) on the history of phage therapy and why it is regaining interest as multidrug-resistant infections rise. It compares phage therapy with chemical antibiotics and their

Case report from the Eliava Phage Therapy Center in Tbilisi of a 16-year-old with Netherton syndrome, atopic diathesis and serious staphylococcal infections, with allergy to multiple antibiotics. Treatment with several antistaphylococcal ph

Article by Jean-Paul Pirnay and colleagues in Pharmaceutical Research, published online on 10 November 2010, whose title frames the phage therapy paradigm as a choice between prêt-à-porter (ready-made) and sur-mesure (tailor-made). Pharmace

Pharokka is a Python tool, installable through bioconda, that annotates bacteriophage genomes easily, rapidly and consistently with standards-compliant outputs, taking under 5 minutes for an average 50-kb phage genome. Its authors built it

Vivek Mutalik shares a new Phage Foundry preprint comparing host requirements and entry routes for single-strand RNA and filamentous DNA phages in E. coli. Vivek Mutalik / Phages KIPRE

PhageScanner is a reconfigurable machine-learning framework for annotating bacteriophage genomic and metagenomic features, including phage virion proteins. PhageScanner: a reconfigurable machine learning framework for bacteriophage genomic

PhageGE is a graphical platform for exploring bacteriophage genomes, with interactive genomic analysis and visualization tools. PhageGE: an interactive web platform for exploratory analysis and visualization of bacteriophage genomes

The study characterizes P9ly, a lytic enzyme from bacteriophage PSD9. In laboratory experiments, it showed bacteriolytic and bactericidal activity against multidrug-resistant Shigella dysenteriae and Staphylococcus aureus strains; combining

This review surveys emerging bacteriophage approaches across infectious and non-infectious diseases, including phage engineering, delivery strategies, and translational research. Bacteriophage therapy beyond antibiotics: emerging innovation

A Clinical Infectious Diseases case series screened Mycobacterium isolates from 200 patients for phage susceptibility and gave phages intravenously, by aerosolization or both to 20 patients on a compassionate-use basis. No adverse reactions

The article outlines a proposed Global Phage Fund that would link revenue from phage products with long-term support for discovery, development, manufacturing standards, regulatory alignment and equitable global access. Sebastian Leptihn