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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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  • Tulane Ventures invests $250,000 in Biophoundry to advance engineered phage therapies

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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesDec 18, 2020

    To use phages as therapeutic agents, ensuring phages reach the site of infection is key. Belinda Loh (Zhejiang University, Ch

    To use phages as therapeutic agents, ensuring phages reach the site of infection is key. Belinda Loh (Zhejiang University, China) and colleagues published a review article unfolding numerous approaches for phage delivery, including methods

    UpdatesFormulationPhage encapsulationReview
  2. UpdatesDec 18, 2020

    Bryan Lenneman (Massachusetts Institute of Technology) and colleagues published a review on phage engineering approaches to r

    Bryan Lenneman (Massachusetts Institute of Technology) and colleagues published a review on phage engineering approaches to redirect specificity and reduce resistance development. They also describe the application of designer phages as gen

    UpdatesPhage engineeringReviewSynthetic biology
  3. UpdatesDec 11, 2020

    The International Society for Viruses of Microorganisms has announced their newly elected executive board members for 2021-20

    The International Society for Viruses of Microorganisms has announced their newly elected executive board members for 2021-2022! Congratulations to Rob Lavigne (President), Zuzanna Drulis-Kawa (President-elect), Andrew Millard (Vice-Presid

    UpdatesCommunityElectionScientific Society
  4. UpdatesDec 11, 2020

    Contrary to what we announced last week, we've had to postpone PHAVES 11 with Dr. Iredell until 2021. Sorry to have gotten yo

    Contrary to what we announced last week, we've had to postpone PHAVES 11 with Dr. Iredell until 2021. Sorry to have gotten your hopes up! We'll see you back in the new year for season 2 — thanks for an awesome first 10 episodes in 2020! Reg

    UpdatesCommunityVirtual EventPHAVES
  5. UpdatesDec 11, 2020

    The 23rd Congress of the International Society for Aerosols in Medicine (ISAM) will be held in Boise, Idaho from 22nd to 26th

    The 23rd Congress of the International Society for Aerosols in Medicine (ISAM) will be held in Boise, Idaho from 22nd to 26th May 2021. The scientific agenda is focusing on the current understanding of pulmonary disease, viral transmission

    UpdatesCommunityConferenceRespiratory medicine
  6. UpdatesDec 11, 2020

    Eleanor Townsend and Eleanor Jameson (University of Warwick) are editing a special issue titled “Phage-Host Interaction in th

    Eleanor Townsend and Eleanor Jameson (University of Warwick) are editing a special issue titled “Phage-Host Interaction in the Gut Microbiome and Their Impacts on Human Health and Disease” in MDPI’s International Journal of Environmental Re

    UpdatesCommunitySpecial IssueGut phageome
  7. UpdatesDec 11, 2020

    BiomX analyzed a set of colorectal cancer tumour samples from patients, and found that 80% contained Fusobacterium nucleatum,

    BiomX analyzed a set of colorectal cancer tumour samples from patients, and found that 80% contained Fusobacterium nucleatum, which BiomX has been engineering phages to target. BiomX's phages are designed to deliver payloads that make tumou

    UpdatesBiotech newsPhages and cancer
  8. UpdatesDec 11, 2020

    UC San Diego has detailed the journey to recovery of another patient who has benefitted from the use of phage therapy. The ca

    UC San Diego has detailed the journey to recovery of another patient who has benefitted from the use of phage therapy. The case involved Maria Madrigal, a polycystic kidney disease (and kidney transplant) patient who suffered from recurrent

    UpdatesPhage TherapyPress Release
  9. UpdatesDec 11, 2020

    Katarzyna Danis-Wlodarczyk (Ohio State University) and colleagues published a new preprint on the antagonistic effect of coli

    Katarzyna Danis-Wlodarczyk (Ohio State University) and colleagues published a new preprint on the antagonistic effect of colistin and ciprofloxacin on bactericidal, bacteriolytic, and virion-production activities of P. aeruginosa podovirus

    UpdatesPhage-antibiotic synergyPreprint
  10. UpdatesDec 11, 2020

    Diana Pires (University of Minho) and colleagues published a review article describing the present-day challenges and opportu

    Diana Pires (University of Minho) and colleagues published a review article describing the present-day challenges and opportunities in phage therapy, by analyzing the outcomes of trials and case reports done to date. Along with the current

    UpdatesPhage TherapyReview
  11. UpdatesDec 11, 2020

    Tolulope Oduselu (Ibadan Bacteriophage Research Team, University of Ibadan) and colleagues recently published their second re

    Tolulope Oduselu (Ibadan Bacteriophage Research Team, University of Ibadan) and colleagues recently published their second review article entitled "Expanding the Frontiers of Bacterial Diagnosis through Bacteriophage Biotechnology". They re

    UpdatesDiagnosticsReview
  12. UpdatesDec 4, 2020

    The fourth iVoM event will be Thursday, December 17, 7pm GMT, and the theme will be "Virus-host interaction: molecular mechan

    The fourth iVoM event will be Thursday, December 17, 7pm GMT, and the theme will be "Virus-host interaction: molecular mechanisms". Talks: - New discoveries on the immune system of bacteria — Rotem Sorek - The regulation and activity of Cl

    UpdatesCommunityVirtual EventViruses of microbesiVoM
  13. UpdatesDec 4, 2020

    My name is Tom Ireland and I'm a science writer based in the UK working on a popular-science book about phages. Under contrac

    My name is Tom Ireland and I'm a science writer based in the UK working on a popular-science book about phages. Under contract with a major publisher, the book aims to bring the wonder of phages to a mass audience, telling the fascinating h

    UpdatesCommunityScience communicationSeeking to interview researchers
  14. UpdatesDec 4, 2020

    The fourth iVoM event will be Thursday, December 17, 7pm GMT, and the theme will be "Virus-host interaction: molecular mechan

    The fourth iVoM event will be Thursday, December 17, 7pm GMT, and the theme will be "Virus-host interaction: molecular mechanisms". Talks: - New discoveries on the immune system of bacteria — Rotem Sorek - The regulation and activity of Cl

    UpdatesCommunityVirtual EventViruses of microbesiVoM
  15. UpdatesDec 4, 2020

    The recording for iVoM #2 (Virus Structure and Function with Petr Leiman, Kristin Parent and Pascale Boulanger) has been post

    The recording for iVoM #2 (Virus Structure and Function with Petr Leiman, Kristin Parent and Pascale Boulanger) has been posted on the VoM 2020 Youtube channel!

    UpdatesCommunityRecordingVirtual Event
  16. UpdatesDec 4, 2020

    Two upcoming phage webinars organized by the Mayo Clinic College of Medicine and Science: 1) From Petri Dish to Patient: Myco

    Two upcoming phage webinars organized by the Mayo Clinic College of Medicine and Science: 1) From Petri Dish to Patient: Mycobacteriophages and Their Therapeutic Potential (December 8): Register here. 2) Phage and Antibiotics: Induction of

    UpdatesCommunityVirtual Event
  17. UpdatesDec 4, 2020

    This week included Giving Tuesday, and some of you likely donated to Phages for Global Health (PGH). A message from the PGH t

    This week included Giving Tuesday, and some of you likely donated to Phages for Global Health (PGH). A message from the PGH team: "Thank you so much for your gifts yesterday — between your contributions and matching funds we raised over $18

    UpdatesCommunityAntibiotic resistanceDonatePhage Therapy
  18. UpdatesDec 4, 2020

    Diane Shader Smith and Mark Smith have established Mallory's Legacy Fund. Their daughter Mallory was one of the first cystic

    Diane Shader Smith and Mark Smith have established Mallory's Legacy Fund. Their daughter Mallory was one of the first cystic fibrosis patients to receive phage therapy (and she inspired Phage Directory's start!). Donations will support phag

    UpdatesDonatePhage Therapy
  19. UpdatesDec 4, 2020

    Dr. David Pride (IPATH, UCSD) wrote a great Scientific American article on the complexity of viruses and the human body. He t

    Dr. David Pride (IPATH, UCSD) wrote a great Scientific American article on the complexity of viruses and the human body. He talks about the tricky tasks of mapping where they are and how they spread, and managing the bad ones while exploiti

    UpdatesScience communicationVirome
  20. UpdatesDec 4, 2020

    PhagoMed's synthetic phage lysin platform for treatment of bacterial vaginosis came in second place (and won 20,000 Euro) in

    PhagoMed's synthetic phage lysin platform for treatment of bacterial vaginosis came in second place (and won 20,000 Euro) in the European Institute of Innovation and Technology's 2020 Health Catapult contest.

    UpdatesAwardLysins
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