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  1. UpdatesApr 18, 2025

    Amalie Høgh Eichler (University of Copenhagen) and colleagues published a new paper on PQS stability in phage lysates, showin

    Amalie Høgh Eichler (University of Copenhagen) and colleagues published a new paper on PQS stability in phage lysates, showing PQS is highly stable in phage lysates for up to a year and can induce quorum sensing responses when carried over,

    UpdatesResearch paperPhage-host interactionsQuorum sensing
  2. UpdatesOct 13, 2023

    Kaat Schroven (KU Leuven) and colleagues discovered that the phage protein PIT2 directly interacts with the LasR T2SS effecto

    Kaat Schroven (KU Leuven) and colleagues discovered that the phage protein PIT2 directly interacts with the LasR T2SS effector, interfering with P. aeruginosa quorum sensing and attenuating virulence, inspiring a new potential phage-encoded

    UpdatesPhage-encoded proteinsPhage-host interactionsQuorum Sensing
  3. UpdatesSep 22, 2023

    Jingxian Yang and colleagues have discovered that agr (quorum sensing) induction reduces expression of tarM (which encodes a

    Jingxian Yang and colleagues have discovered that agr (quorum sensing) induction reduces expression of tarM (which encodes a glycosyltransferase responsible for modification of the major S. aureus phage receptor). This allows lytic phage St

    UpdatesResearch paperPhage susceptibilityQuorum sensing
  4. UpdatesAug 27, 2021

    Nicole Rutbeek (University of Manitoba, Canada) and colleagues published a research article in JBC on the molecular mechanism

    Nicole Rutbeek (University of Manitoba, Canada) and colleagues published a research article in JBC on the molecular mechanism of quorum sensing inhibition in Streptococcus by the phage protein paratox. They demonstrated an example of conver

    UpdatesPhage proteinsQuorum sensingResearch paper
  5. UpdatesJan 15, 2021

    Megha Shah (University of Toronto) and colleagues published a new paper in Molecular Cell showing how a phage-encoded anti-ac

    Megha Shah (University of Toronto) and colleagues published a new paper in Molecular Cell showing how a phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa.

    UpdatesQuorum sensingResearch paper

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