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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesApr 19, 2019

    Kathryn Kauffman and Martin Polz of MIT have developed new ways of streamlining phage propagation and titration methods to sa

    Kathryn Kauffman and Martin Polz of MIT have developed new ways of streamlining phage propagation and titration methods to save us all time and materials. You can also find the protocols here on Protocols.io!

    UpdatesResearchProtocols
  2. UpdatesApr 19, 2019

    A new paper by Gerlach et al. shows that a phage gene can help MRSA evade immune defenses. See also this commentary on the pa

    A new paper by Gerlach et al. shows that a phage gene can help MRSA evade immune defenses. See also this commentary on the paper.

    UpdatesResearch
  3. UpdatesApr 19, 2019

    Sarah Kronheim et al. published a paper in Nature this week on a new mechanism of chemical phage defense in Streptomyces. Her

    Sarah Kronheim et al. published a paper in Nature this week on a new mechanism of chemical phage defense in Streptomyces. Here's a News and Views piece by Martha Clokie and an Ars Technica piece on the work.

    UpdatesResearch
  4. UpdatesApr 19, 2019

    Christian Møller-Olsen et al. just published an article in Scientific Reports showing that an E. coli phage can kill its host

    Christian Møller-Olsen et al. just published an article in Scientific Reports showing that an E. coli phage can kill its host intracellularly, and that it kills more efficiently when human bladder epithelial cells are present. This corrobor

    UpdatesResearchPhage Biology
  5. UpdatesApr 19, 2019

    Lytic phages are usually thought to be best for therapy, but this recent review by Rodrigo Monteiro et al. makes a case for g

    Lytic phages are usually thought to be best for therapy, but this recent review by Rodrigo Monteiro et al. makes a case for giving temperate phages a second look.

    UpdatesResearch
  6. UpdatesApr 18, 2019

    Sooyeon Song and colleagues have published a new paper showing that E. coli employs both active (lytic and temperate) and ina

    Sooyeon Song and colleagues have published a new paper showing that E. coli employs both active (lytic and temperate) and inactive phages (a cryptic prophage) to discriminate between nearby strains and control cell-cell contact according to

    UpdatesResearchPhage Biology
  7. UpdatesMar 28, 2019

    Johanna Sweere and colleagues just published a very exciting paper today in Science! A temperate filamentous phage of Pseudom

    Johanna Sweere and colleagues just published a very exciting paper today in Science! A temperate filamentous phage of Pseudomonas aeruginosa dampens the immune response against P. aeruginosa, which leads to increased P. aeruginosa virulence

    UpdatesResearchFilamentous phagePhage-Immune Interactions
  8. UpdatesMar 28, 2019

    This week, several exciting new papers on the evolution of CRISPR-Cas systems were published. One, by Amelia McKitterick and

    This week, several exciting new papers on the evolution of CRISPR-Cas systems were published. One, by Amelia McKitterick and colleagues from the Seed lab at UC Berkeley, shows how a phage-encoded CRISPR-Cas system interferes with an anti-ph

    UpdatesResearchCRISPRPhage
  9. UpdatesMar 8, 2019

    Marco Cafora and colleagues have developed a zebrafish model of cystic fibrosis and used it to show that phage therapy can tr

    Marco Cafora and colleagues have developed a zebrafish model of cystic fibrosis and used it to show that phage therapy can treat Pseudomonas aeruginosa (and modulate immune response in the fish). This is the first time that phage therapy ha

    UpdatesResearchPhage TherapyAnimal Model
  10. UpdatesFeb 22, 2019

    A new virome twin study! J. Leonardo Moreno-Gallego and colleagues show that virome and microbiome diversity correlate, and i

    A new virome twin study! J. Leonardo Moreno-Gallego and colleagues show that virome and microbiome diversity correlate, and in contrast to a prior study, adult twins DO have more similar viromes than unrelated individuals. They suggest that

    UpdatesGut viromeGut microbiomeResearch
  11. UpdatesFeb 15, 2019

    Stephen Wandro and colleagues at the University of California, Irvine have published a new paper on Enterococcus faecium phag

    Stephen Wandro and colleagues at the University of California, Irvine have published a new paper on Enterococcus faecium phage evolution. His experiments, which he presented at Kisaco Research's North American Microbiome Congress last week,

    UpdatesResearchUseful method
  12. UpdatesFeb 8, 2019

    Guy Schleyer and colleagues published a new paper on "in-plaque" mass spec imaging to visualize what happens during (algal) v

    Guy Schleyer and colleagues published a new paper on "in-plaque" mass spec imaging to visualize what happens during (algal) viral infection. Here's the original paper and a blog post on the work.

    UpdatesNovel methodResearch
  13. UpdatesJan 17, 2019

    Jee-Hwan Oh and colleagues published a paper on how certain dietary sugars promote Lactobacillus phage production in the mous

    Jee-Hwan Oh and colleagues published a paper on how certain dietary sugars promote Lactobacillus phage production in the mouse gut.

    UpdatesResearchPhage BiologyGut
  14. UpdatesDec 21, 2018

    Justin Silpe and Bonnie Bassler discovered that a Vibrio cholerae phage senses its host’s quorum sensing molecules and lyses

    Justin Silpe and Bonnie Bassler discovered that a Vibrio cholerae phage senses its host’s quorum sensing molecules and lyses only when enough hosts are present in the surrounding area. By engineering this system, they got phages to lyse in

    UpdatesResearch
  15. UpdatesDec 14, 2018

    Christian Møller-Olsen et al. just published an article in Scientific Reports showing that an E. coli phage can kill its host

    Christian Møller-Olsen et al. just published an article in Scientific Reports showing that an E. coli phage can kill its host intracellularly, and that it kills more efficiently when human bladder epithelial cells are present. This corrobor

    UpdatesResearchPhage Biology
  16. UpdatesDec 14, 2018

    Lytic phages are usually thought to be best for therapy, but this recent review by Rodrigo Monteiro et al. makes a case for g

    Lytic phages are usually thought to be best for therapy, but this recent review by Rodrigo Monteiro et al. makes a case for giving temperate phages a second look.

    UpdatesResearch
  17. UpdatesDec 7, 2018

    Sarah Kronheim et al. published a paper in Nature this week on a new mechanism of chemical phage defense in Streptomyces. Her

    Sarah Kronheim et al. published a paper in Nature this week on a new mechanism of chemical phage defense in Streptomyces. Here's a News and Views piece by Martha Clokie and an Ars Technica piece on the work.

    UpdatesResearch
  18. UpdatesNov 30, 2018

    A new paper by Gerlach et al. shows that a phage gene can help MRSA evade immune defenses. See also this commentary on the pa

    A new paper by Gerlach et al. shows that a phage gene can help MRSA evade immune defenses. See also this commentary on the paper.

    UpdatesResearch
  19. UpdatesNov 30, 2018

    Kathryn Kauffman and Martin Polz of MIT have developed new ways of streamlining phage propagation and titration methods to sa

    Kathryn Kauffman and Martin Polz of MIT have developed new ways of streamlining phage propagation and titration methods to save us all time and materials. You can also find the protocols here on Protocols.io!

    UpdatesResearchProtocols
  20. UpdatesNov 8, 2018

    How much should we worry about phage-induced spreading of antibiotic resistance? This review by Clara Torres-Barceló lays out

    How much should we worry about phage-induced spreading of antibiotic resistance? This review by Clara Torres-Barceló lays out some contrasting viewpoints and data on the matter.

    UpdatesAntibiotic ResistanceResearch
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