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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesNov 22, 2019

    Ushanandini Mohanraj (University of Helsinki) and colleagues have published a paper showing a screen they've developed to ide

    Ushanandini Mohanraj (University of Helsinki) and colleagues have published a paper showing a screen they've developed to identify hypothetical phage proteins with antibacterial activity. They've used it to identify four Yersinia phage prot

    UpdatesResearchMethodsAssigning functions to phage genes
  2. UpdatesNov 22, 2019

    Mainstream news outlets are covering antibiotic resistance as a result of the two major antibiotic resistance reports just re

    Mainstream news outlets are covering antibiotic resistance as a result of the two major antibiotic resistance reports just released (which we covered last week). CBS News gets into why the system for antimicrobial development is broken. Glo

    UpdatesNewsAntibiotic Resistance
  3. UpdatesNov 20, 2019

    Seeking phage titration methods & help

    Emmanuel Nnadi, Plateau State University We have been attempting to get the titre of our phage but don't seem to know where we are getting it wrong. What's your preferred protocol? We use the double-layer plaque assay and a McFarlands stand

    UpdatesCommunitySeeking guidanceProtocols
  4. UpdatesNov 20, 2019

    Seeking phage titration methods & help

    Emmanuel Nnadi, Plateau State University We have been attempting to get the titre of our phage but don't seem to know where we are getting it wrong. What's your preferred protocol? We use the double-layer plaque assay and a McFarlands stand

    UpdatesCommunitySeeking guidanceProtocols
  5. UpdatesNov 15, 2019

    Felix Biotechnology is a new phage company using phages to target antibiotic resistant bacteria based on their mechanism of a

    Felix Biotechnology is a new phage company using phages to target antibiotic resistant bacteria based on their mechanism of antibiotic resistance (working with Yale University). They just won this year's Falling Walls Venture competition in

    UpdatesBiotechAwardPhage Therapy
  6. UpdatesNov 15, 2019

    Boston PFU (Phage Fanatics United) First Meetup!

    The first meeting of Boston PFU (Phage Fanatics United) will be Thursday, Dec. 5, 2019 at the Countway Medical Library, Harvard Medical School. Find details and join the mailing list here! This is a social and general meeting, and is open t

    UpdatesCommunityPhage meetupPhageSocialCollaboration
  7. UpdatesNov 15, 2019

    Boston PFU (Phage Fanatics United) First Meetup!

    The first meeting of Boston PFU (Phage Fanatics United) will be Thursday, Dec. 5, 2019 at the Countway Medical Library, Harvard Medical School. Find details and join the mailing list here! This is a social and general meeting, and is open t

    UpdatesCommunityPhage meetupPhageSocialCollaboration
  8. UpdatesNov 15, 2019

    Yi Duan (UCSD) and colleagues have published an incredibly exciting paper showing that cytotoxin-secreting Enterococcus faeca

    Yi Duan (UCSD) and colleagues have published an incredibly exciting paper showing that cytotoxin-secreting Enterococcus faecalis in the mouse gut is a cause of alcohol-induced liver disease in mice. Most excitingly, they used phages to targ

    UpdatesLiver diseaseResearchPhage TherapyMicrobiome editing
  9. UpdatesNov 15, 2019

    Shelley Gibson (Baylor College of Medicine) and colleagues have published a paper describing the generation of phage librarie

    Shelley Gibson (Baylor College of Medicine) and colleagues have published a paper describing the generation of phage libraries against three pathogens: E. coli, P. aeruginosa and Enterobacter cloacae. They've characterized the phages system

    UpdatesPhage libraryResearchPhage Therapy
  10. UpdatesNov 15, 2019

    Diane Shader Smith wrote a beautiful article commemorating the two-year anniversary of her daughter Mallory’s passing. Mallor

    Diane Shader Smith wrote a beautiful article commemorating the two-year anniversary of her daughter Mallory’s passing. Mallory passed away due to drug-resistant Burkholderia and cystic fibrosis. Diane remarks that Mallory's legacy lives on

    UpdatesIn memoryPhage TherapyCystic Fibrosis
  11. UpdatesNov 15, 2019

    BiomX just presented preclinical data on its development of a phage cocktail active against Klebsiella pneumoniae strains cor

    BiomX just presented preclinical data on its development of a phage cocktail active against Klebsiella pneumoniae strains correlated with primary sclerosing cholangitis (PSC) severity. PSC is a liver disease with no FDA-approved treatment t

    UpdatesBiotechPhage TherapyPreclinical dataPhage cocktail
  12. UpdatesNov 15, 2019

    One of Intralytix's phage products, EcoShield (which targets E. coli O157:H7), has been approved by the FDA to be used more b

    One of Intralytix's phage products, EcoShield (which targets E. coli O157:H7), has been approved by the FDA to be used more broadly. Now it can be used on ground beef (plus other meat cuts and on carcasses). Previously, it could only be use

    UpdatesBiotechPhages in foodRegulation
  13. UpdatesNov 15, 2019

    The Open Health Systems Colloquium and the International Bacteriophage Research Consortium will be hosting a lecture and pane

    The Open Health Systems Colloquium and the International Bacteriophage Research Consortium will be hosting a lecture and panel discussion on "Charting a Path Toward Bacteriophage Therapy" on Nov. 19 from 6-8:30 PM at the India International

    UpdatesPanelPhage TherapyLive stream
  14. UpdatesNov 15, 2019

    Edze Westra of the University of Exeter has been awarded the 2020 Fleming Prize from the Microbiology Society for his work on

    Edze Westra of the University of Exeter has been awarded the 2020 Fleming Prize from the Microbiology Society for his work on CRISPR-CAS molecular mechanisms and evolutionary ecology. This award is the oldest prize awarded by the Microbiolo

    UpdatesAwardMicrobiologyCRISPR
  15. UpdatesNov 14, 2019

    BiomX just presented preclinical data on its development of a phage cocktail active against Klebsiella pneumoniae strains cor

    BiomX just presented preclinical data on its development of a phage cocktail active against Klebsiella pneumoniae strains correlated with primary sclerosing cholangitis (PSC) severity. PSC is a liver disease with no FDA-approved treatment t

    UpdatesBiotechPhage TherapyPreclinical dataPhage cocktail
  16. UpdatesNov 13, 2019

    Diane Shader Smith wrote a beautiful article commemorating the two-year anniversary of her daughter Mallory’s passing. Mallor

    Diane Shader Smith wrote a beautiful article commemorating the two-year anniversary of her daughter Mallory’s passing. Mallory passed away due to drug-resistant Burkholderia and cystic fibrosis. Diane remarks that Mallory's legacy lives on

    UpdatesIn memoryPhage TherapyCystic Fibrosis
  17. UpdatesNov 13, 2019

    One of Intralytix's phage products, EcoShield (which targets E. coli O157:H7), has been approved by the FDA to be used more b

    One of Intralytix's phage products, EcoShield (which targets E. coli O157:H7), has been approved by the FDA to be used more broadly. Now it can be used on ground beef (plus other meat cuts and on carcasses). Previously, it could only be use

    UpdatesBiotechPhages in foodRegulation
  18. UpdatesNov 13, 2019

    Shelley Gibson (Baylor College of Medicine) and colleagues have published a paper describing the generation of phage librarie

    Shelley Gibson (Baylor College of Medicine) and colleagues have published a paper describing the generation of phage libraries against three pathogens: E. coli, P. aeruginosa and Enterobacter cloacae. They've characterized the phages system

    UpdatesPhage libraryResearchPhage Therapy
  19. UpdatesNov 13, 2019

    Yi Duan (UCSD) and colleagues have published an incredibly exciting paper showing that cytotoxin-secreting Enterococcus faeca

    Yi Duan (UCSD) and colleagues have published an incredibly exciting paper showing that cytotoxin-secreting Enterococcus faecalis in the mouse gut is a cause of alcohol-induced liver disease in mice. Most excitingly, they used phages to targ

    UpdatesLiver diseaseResearchPhage TherapyMicrobiome editing
  20. UpdatesNov 13, 2019

    Edze Westra of the University of Exeter has been awarded the 2020 Fleming Prize from the Microbiology Society for his work on

    Edze Westra of the University of Exeter has been awarded the 2020 Fleming Prize from the Microbiology Society for his work on CRISPR-CAS molecular mechanisms and evolutionary ecology. This award is the oldest prize awarded by the Microbiolo

    UpdatesAwardMicrobiologyCRISPR
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