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  • PRAN Virtual Undergraduate Phage Research Symposium 2026: call for abstractsOct 23, 2026

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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesJan 1, 2021

    Kristen LeGault (University of California, Berkeley) and colleagues published a new preprint showing how temporal shifts in a

    Kristen LeGault (University of California, Berkeley) and colleagues published a new preprint showing how temporal shifts in antibiotic resistance elements govern virus-pathogen conflicts in Vibrio cholerae recovered from clinical samples. T

    UpdatesPhage defense systemsPhage-host interactionsPreprintResearch paper
  2. UpdatesOct 16, 2020

    Charles Bernard (CNRS, France) and colleagues published a new paper in the ISME Journal describing their identification of a

    Charles Bernard (CNRS, France) and colleagues published a new paper in the ISME Journal describing their identification of a new communication system that may regulate host defense mechanisms (similar to the arbitrium system) in Bacillus ph

    UpdatesPhage defense systemsResearch paper
  3. UpdatesSep 25, 2020

    Viperins are known to function in the eukaryotic antiviral response, and now they've been found in prokaryotes. Aude Bernheim

    Viperins are known to function in the eukaryotic antiviral response, and now they've been found in prokaryotes. Aude Bernheim (Weizmann Institute of Science) and colleagues published a new paper in Nature on prokaryotic viperins, which prot

    UpdatesPhage defense systemsResearch paper
  4. UpdatesSep 4, 2020

    Linyi Gao (Howard Hughes Medical Institute, Cambridge, MA) and colleagues published a new paper in Science describing their d

    Linyi Gao (Howard Hughes Medical Institute, Cambridge, MA) and colleagues published a new paper in Science describing their discovery of 29 new phage-protective gene cassettes, many of which incorporate enzymatic activities not previously i

    UpdatesPhage defense systemsResearch paper
  5. UpdatesAug 28, 2020

    Cyclic-oligonucleotide-based anti-phage signalling systems (CBASS) share ancestry with an innate immune pathway in animals. A

    Cyclic-oligonucleotide-based anti-phage signalling systems (CBASS) share ancestry with an innate immune pathway in animals. Adi Millman (Weizmann Institute of Science, Israel) and colleagues published a new paper in Nature Microbiology on C

    UpdatesPhage defense systemsResearch paper
  6. UpdatesJul 17, 2020

    Siân Owen (Harvard Medical School) and colleagues published a new preprint on a new prophage-encoded defense protein that sim

    Siân Owen (Harvard Medical School) and colleagues published a new preprint on a new prophage-encoded defense protein that simultaneously suppresses phage epidemics in a population (through abortive infection) and provides self-immunity to t

    UpdatesPhage defense systemsPreprintProphage
  7. UpdatesJun 26, 2020

    Retrons are bacterial genetic elements comprised of a reverse transcriptase (RT) and a non-coding RNA, but their functions ha

    Retrons are bacterial genetic elements comprised of a reverse transcriptase (RT) and a non-coding RNA, but their functions have been unknown for decades. Adi Millman (Weizmann Institute of Science, Israel) and colleagues published a new pre

    UpdatesPhage defense systemsPhage-host interactionsResearch paper
  8. JobsJun 19, 2020

    The Bikard Lab (Institut Pasteur, Paris) is hiring a postdoc to study the properties of Cas proteins in bacteria, their inter

    The Bikard Lab (Institut Pasteur, Paris) is hiring a postdoc to study the properties of Cas proteins in bacteria, their interaction with DNA repair pathways, and the mechanism and evolution of CRISPR-Cas systems as phage defense systems

    JobsCRISPRPhage defense systemsPost Doc
  9. UpdatesJun 5, 2020

    Shannon Slattery (University of Limerick, Ireland) and colleagues published a new paper in Scientific Reports describing the

    Shannon Slattery (University of Limerick, Ireland) and colleagues published a new paper in Scientific Reports describing the isolation of a Proteus mirabilis strain from wastewater harbouring an integrative conjugative element (ICE) contain

    UpdatesPhage defense systemsResearch paper
  10. UpdatesMay 15, 2020

    Shweta Karambelkar (Indian Institute of Science) and colleagues published a interesting report on how phage Mu uniquely prote

    Shweta Karambelkar (Indian Institute of Science) and colleagues published a interesting report on how phage Mu uniquely protects its DNA from diverse host defense systems in Nucleic Acids Research. They characterized Mu's "Mom" protein, whi

    UpdatesMolecular BiologyPhage defense systemsResearch paper
  11. UpdatesMay 15, 2020

    Oliver Bezuidt (University of Pretoria, South Africa) and colleagues published a new paper in mSystems that sheds light on An

    Oliver Bezuidt (University of Pretoria, South Africa) and colleagues published a new paper in mSystems that sheds light on Antarctic phage-host interactions. Their metagenomic analysis picked up DISARM, BREX and CRISPR-Cas defense systems i

    UpdatesMetagenomicsMetaviromicsPhage defense systemsResearch paper
  12. UpdatesMay 14, 2020

    Oliver Bezuidt (University of Pretoria, South Africa) and colleagues published a new paper in mSystems that sheds light on An

    Oliver Bezuidt (University of Pretoria, South Africa) and colleagues published a new paper in mSystems that sheds light on Antarctic phage-host interactions. Their metagenomic analysis picked up DISARM, BREX and CRISPR-Cas defense systems i

    UpdatesMetagenomicsMetaviromicsPhage defense systemsResearch paper
  13. UpdatesMay 14, 2020

    Shweta Karambelkar (Indian Institute of Science) and colleagues published a interesting report on how phage Mu uniquely prote

    Shweta Karambelkar (Indian Institute of Science) and colleagues published a interesting report on how phage Mu uniquely protects its DNA from diverse host defense systems in Nucleic Acids Research. They characterized Mu's "Mom" protein, whi

    UpdatesMolecular BiologyPhage defense systemsResearch paper
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