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Nicolas Kieffer (Universidad Complutense de Madrid, Spain) and colleagues investigated the role of mobile integrons in phage defense systems, showing that integrons can confer multiphage resistance and limit prophage activation.

Karen Maxwell (University of Toronto) has been awarded the Arthur B. McDonald Fellowship for her research into antiviral defenses, which uncovered novel CRISPR inhibitors (anti-CRISPRs), according to a recent announcement by NSERC (Canada).

The Canadian Society of Microbiologists conference (CSM) is hosting a phage session (Bacteriophage and bacterial defense systems). This year, the conference is hosted in Halifax from June 25th-28th, and the abstract deadline is April 17th.

This PhD project, co-supervised by Tiffany Taylor (University of Bath), Edze Westra (University of Exeter), and Andrew Preston (University of Bath), with collaborators Ben Ashby (Simon Fraser University) will study the interplay between a n

Adi Millman et al. published a new paper in Cell Host & Microbe entitled An expanded arsenal of immune systems that protect bacteria from phages. They report the discovery of 21 defense systems that protect bacteria from phages, based on co

The Molecular Microbiology lab at Washington University is hiring a staff scientist to characterize new phage defense mechanisms.

In this Nature Microbiology paper, Christopher N. Vassallo and colleagues used an experimental selection scheme agnostic to genomic context to identify phage defence systems in 71 diverse E. coli strains. They found 21 conserved defence sys

You probably know a lot of antiphage defense systems that rely on proteins or nucleic acids. But what about the role of small molecules in antiphage defense? — Aël Hardy, describing his new paper, “Antiphage small molecules produced by bact

Paper: Mucin induces CRISPR-Cas defense in an opportunistic pathogen.

Paper: Mucin induces CRISPR-Cas defense in an opportunistic pathogen.

Paper: Cleavage of viral DNA by restriction endonucleases stimulates the type II CRISPR-Cas immune response. Also check out this Spotlight on the paper.

Preprint: Bacteriophages antagonize cGAS-like immunity in bacteria

Paper: A mobile restriction–modification system provides phage defence and resolves an epigenetic conflict with an antagonistic endonuclease

Preprint: Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion — Jeremy Garb et al.

Preprint: Class I DISARM provides anti-phage and anti-conjugation activity by unmethylated DNA recognition.

PhD position investigating prokaryotic defence and phage anti-defence systems at the University of Southampton

Siân Owen (Harvard Medical School, USA) and colleagues published a new paper in Cell Host & Microbe showing prophages encode phage-defense systems with cognate self-immunity.

Siân Owen (Harvard Medical School) and colleagues published a new paper in Cell Host & Microbe showing prophages encode phage-defense systems with cognate self-immunity. Check out this awesome Twitter thread by Jay Hinton about the discover

Microviridae (a family of tiny ssDNA phages) tend to dominate human viromes, yet little is known about them. Paul Kirchberger (UT Austin) and colleagues published a new paper in PNAS describing how microviruses encode defensive hypervariabl

Bridget Watson (University of Exeter) and colleagues published a new review in Cell Host & Microbe on coevolution between bacterial CRISPR-Cas systems and their phages. They discuss when and why CRISPR-Cas immunity against phages evolves, a