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Ryan Cook (Quadram Institute Bioscience, UK) and colleagues have identified many phages that repurpose stop codons to encode amino acids. They re-annotated these sequences with modified versions of Pharokka and Prokka to automatically predi

Mihály Koncz (HUN-REN Biological Research Centre, Szeged, Hungary) demonstrate the utility of pathogen genomic surveillance combined with high-throughput phage typing for enabling phage therapy. Their analysis reveals that a few strain type

In an upcoming course in Lyon, France (Nov 12-13 2024), the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) will explore current clinical experiences, compassionate use protocols, cohort studies, and ongoing clini

In an upcoming course in Lyon, France (Nov 12-13 2024), the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) will explore current clinical experiences, compassionate use protocols, cohort studies, and ongoing clini

In an upcoming course in Lyon, France (Nov 12-13 2024), the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) will explore current clinical experiences, compassionate use protocols, cohort studies, and ongoing clini

In an upcoming course in Lyon, France (Nov 12-13 2024), the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) will explore current clinical experiences, compassionate use protocols, cohort studies, and ongoing clini

The study predicted 76 INPHARED genomes and 712 Unified Human Gut Virome Catalogue vOTUs that repurpose a stop codon to encode an amino acid, and re-annotated them with modified Pharokka-gv and Prokka-gv tools. For sequences predicted to re

PharaCon applies conditional BERT to phage identification, incorporating labels during pre-training and fine-tuning. The authors evaluated the framework on simulated sequences and real metagenomic contigs. bioRxiv

New phage conference alert — this time in South America!! Phage researchers at the Universidad de los Andes invite the international phage community to Phage Option Congress 2024 (Dec 4-6, 2024 in Cartagena, Colombia). This will be the 3r

Registration is now open for the 2024 International Soil Virus Conference! Soil virologists and enthusiasts will gather to explore the multifaceted roles of soil viruses within a One Health framework, with a special focus on meta-omics cha

Lina Zeldovich, an author who grew up in a family of Soviet scientists, published a new book, ‘The Living Medicine: How a Lifesaving Cure Was Nearly Lost—and Why It Will Rescue Us When Antibiotics Fail’. She explores the history and potenti

HYpharm GmbH and the German Center for Infection Research announced that their phage lysin HY-133 has entered phase I clinical trials. HY-133 aims to prevent nasal colonization by MRSA. The trial is conducted at the University Hospital of T

Deepto Mozumdar (University of California, San Francisco) and colleagues have characterized a new lipid-based jumbo phage compartment — a hub for early phage infection. The study explores how phage ΦKZ assembles a vesicle to protect its gen

Khalimat Murtazalieva (European Bioinformatics Institute) and colleagues have discovered 145 phage anti-defence systems (ADSs) that counteract 27 of the 152 known bacterial defence families. They discuss high-throughput approaches which are

Beatriz Beamud (Institut Pasteur) and colleagues have discovered that many bacterial defense systems against phages are encoded by mobile genetic elements, challenging traditional views of bacterial immunity.

In a new preprint, Ritam Das and Janina Rahlff (Friedrich Schiller University Jena, Germany) describe a positive correlation between the number of structural genes and above-average guanine-cytosine (GC) content in phage genomes.

Check out this episode of the Phage Therapy Today podcast, which features Dr. Mercedes Gonzalez from INCATE (an AMR startup funder/accelerator) and Dr. Gregorio Iraola at Kinzbio, an INCATE recipient and founder of a new phage startup in Ur

One hundred personalized phage treatments, combined! Not only did Jean-Paul Pirnay and colleagues at the Queen Astrid Military Hospital in Belgium provide phages for 100 cases, they also published a full analysis of the outcomes! This led N

Katie Wiebe (Cytophage Technologies, Inc) and colleagues have outlined a scalable and efficient production strategy for the ETEC phage ‘Phage75’, which accounts for infection load, MOI, temperature, media, harvest time, and host bacteria (t

Qingquan (Kevin) Chen (Stanford University) and colleagues have demonstrated that filamentous Pf phages of P. aeruginosa hinder antibiotic diffusion through CF sputum via electrostatic binding.