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This week, Esme Brinsden, a recent bio grad from the University of Southampton, shares her experience working on the Phage Collection Project, an early career-led citizen science initiative aimed at advancing phage therapy research. ## What

Eric Nguyen (Stanford University, Arc Institute) and colleagues published a paper on their new machine learning model, Evo, a new generative AI model trained on millions of phage and bacterial genomes for designing new biological sequences

Baptiste Gaborieau (Université Paris Cité, France) and colleagues created a new machine learning model able to predict Escherichia phage-host interactions and design effective phage cocktails using only genomic data.

Ryan Cook and Andrew Millard have announced updates to their INPHARED phage genome database, showing a significant increase in Microviridae genomes (from what looks like one new study).

Léa Ibarlosa (CNRS-Université de Bordeaux, France) and colleagues published a new paper on amyloid signaling in antiphage defense, showing that amyloid proteins Bab and Agp form a novel E. coli antiphage system activating cell death upon in

Joaquín Martínez Martínez (Bigelow Laboratory for Ocean Sciences, Maine) and colleagues published a new paper on viral carbon and nitrogen assimilation by microbes, showing protists and bacteria can obtain significant carbon and nitrogen fr

PrecisionPhage is hiring a Marketing Manager, to develop and execute marketing strategies, create content, and build the brand for their phage-based solutions against antibiotic-resistant infections.

OSPT Ltd in Oxford, England is hiring a Phage Microbiologist R&D Lead, to study phage microbiology and lead medical device development. They will manage experiments, develop SOPs, and drive product innovation.

Phages for Global Health's president, Dr Tobi Nagel, is working in Malaysia for 2 months as part of her Fulbright project on phage therapy regulation systems. Excitingly, the Malaysia Phage Network (MPN) has just launched! The first meetin

Maryn McKenna and Lina Zeldovich held a live Q&A about phage therapy at Emory University. Zeldovich, a Soviet-born scientist-turned-author, discusses her new book "The Living Medicine," which explores the revival of phage therapy as a poten

Scientists from the Institut Pasteur, Inserm, AP-HP and Université Paris Cité trained an AI model that recommends a phage cocktail for a bacterial strain from its genome alone, using 350,000 interactions between 403 E. coli strains and 96 p

This week, NYIT undergrad student Yamini Patel shares insights from Viruses of Microbes 2024 in Australia. She highlights what she learned, from phage therapy with Rob Lavigne, to Colin Hill's insights on crAssphage, to what's new in microb

Why don't we have phage therapy yet? We want to understand why. Come join the fun, with the new Podovirus podcast! 🎙️ Most recent episode: NIAID's Joe Campbell joins as a co-host for an interview with Dr. Gina Suh, Mayo Clinic ID physicia

Chao Liu (Chinese Academy of Sciences) and colleagues published a new paper on phage CRISPR-like regulatory RNAs silencing bacterial immunity, showing how phages use crlRNA mimics to hijack host CRISPR-Cas and abortive infection defenses in

Talia Backman (University of Utah) and colleagues published a new paper on tradeoffs and constraints in tailocin evolution, showing tailocins exhibit extreme target specificity, evolve rapidly, and face tradeoffs between resistance and host

Anthony King wrote a piece for Nature Outlook on bacteria-killing viruses in the gut microbiome, showing that phages are key players in gut ecology but remain difficult to study due to their abundance and diversity.

Susu Jiang (Shenzhen University Medical School, China) and colleagues published a new paper on phage-encoded kinase evading bacterial defenses, showing the JSS1_004 protein phosphorylates multiple bacterial defense systems to enable phage i

Marwan Mahmood Saleh (University of Anbar, Iraq) and colleagues evaluated the lytic efficiency of a three-phage cocktail against multidrug-resistant P. aeruginosa isolates in vitro. The cocktail showed broad activity, including against XDR

Metabolites released from intact, phage-infected Synechococcus strongly attracted the marine bacteria Vibrio alginolyticus and Pseudoalteromonas haloplanktis, especially in early infection, while uninfected cyanobacteria did not. 5'-deoxyad

On 15 November 2024 the board of Portugal's medicines authority INFARMED approved, in Deliberação n.º 112/CD/2024, a guidance note on compounded medicines for phage therapy in hospitals: magistral preparations of bacteriophages made in a ho