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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesMay 19, 2023

    The Leicester Centre for Phage Research celebrated its grand opening/official launch this week!

    The Leicester Centre for Phage Research celebrated its grand opening/official launch this week!

    UpdatesCommunityPhage researchLaunch
  2. UpdatesMay 19, 2023

    Jagdev Singh and colleagues published a clinical trial announcement that will involve a single-arm, open-labelled study inves

    Jagdev Singh and colleagues published a clinical trial announcement that will involve a single-arm, open-labelled study investigating the safety and tolerability of intrabronchial and nebulized phage treatment in children with cystic fibros

    UpdatesClinical TrialCystic fibrosisPhage therapy
  3. UpdatesMay 19, 2023

    Denish Piya and colleagues published a preprint on genome-wide CRISPRi knockdown to map essential elements across whole phage

    Denish Piya and colleagues published a preprint on genome-wide CRISPRi knockdown to map essential elements across whole phage-host genome combinations at once. Their results recapitulate the essential genes determined from decades of analys

    UpdatesPhage-host InteractionsHigh-throughput screenPreprint
  4. UpdatesMay 19, 2023

    David Wishart and colleagues have introduced PHASTEST (PHAge Search Tool with Enhanced Sequence Translation) as a faster and

    David Wishart and colleagues have introduced PHASTEST (PHAge Search Tool with Enhanced Sequence Translation) as a faster and more accurate web server for annotating prophage sequences and bacterial genomes. In standardized tests, PHASTEST o

    UpdatesBioinformatics toolResearch paper
  5. UpdatesMay 19, 2023

    A recent preprint by Michele Mutti and colleagues reveals that phage activity against Staphylococcus aureus is severely impai

    A recent preprint by Michele Mutti and colleagues reveals that phage activity against Staphylococcus aureus is severely impaired in plasma and synovial fluid. Coagulation factors binding to the bacteria form clots that protect them from pha

    UpdatesPhage stabilityPhage-immune interactionsPreprint
  6. UpdatesMay 19, 2023

    Copenhagen-based SNIPR Biome, a CARB-X portfolio company, has developed SNIPR001, a cocktail of CRISPR-armed phages designed

    Copenhagen-based SNIPR Biome, a CARB-X portfolio company, has developed SNIPR001, a cocktail of CRISPR-armed phages designed to target E. coli. A recent release by Robin Berghaus of CARB-X highlights the potential of SNIPR001 to prevent blo

    UpdatesBiotech newsClinical TrialPhage therapyPhages and cancer
  7. UpdatesMay 18, 2023

    UK public attitudes to phage therapy: survey of 787 people

    PLOS ONE survey (N = 787, Prolific) of UK public awareness and acceptance of phage therapy found moderate acceptance, a mean likelihood of 4.71 on a 1-7 scale. Priming participants to think about novel medicines and antibiotic resistance ra

    UpdatesPapersPhage Therapy
  8. UpdatesMay 12, 2023

    Phages for Global Health is currently hosting a workshop in Southeast Asia in collaboration with the UST BEATS Research Group

    Phages for Global Health is currently hosting a workshop in Southeast Asia in collaboration with the UST BEATS Research Group (run by Donna May Papa) in the Philippines. Phage scientists from the Philippines, Indonesia, Vietnam, Sri Lanka,

    UpdatesCommunityPhages for Global HealthPhage workshops
  9. UpdatesMay 12, 2023

    Introducing PhageCast, a new podcast that brings you news and interviews covering the exciting world of phages. Hosted by a g

    Introducing PhageCast, a new podcast that brings you news and interviews covering the exciting world of phages. Hosted by a group of PhD students (David, Maria and Alexandre) from the Azeredo Lab (read about their story, published last week

    UpdatesCommunityPodcast
  10. UpdatesMay 12, 2023

    Congratulations to Evelien Adriaenssens, who has passed her tenure review and become a permanent group leader at The Quadram

    Congratulations to Evelien Adriaenssens, who has passed her tenure review and become a permanent group leader at The Quadram Institute! Evelien has supported/driven so many phage community efforts over the years. She’s taught us all about h

    UpdatesCommunityCongratulationsMilestones
  11. UpdatesMay 12, 2023

    “Resistant bacteria do a lot of taking…” The Center for Disease Control published Diane Shader Smith’s story of her daughter

    “Resistant bacteria do a lot of taking…” The Center for Disease Control published Diane Shader Smith’s story of her daughter Mallory’s battle against a superbug, how phage therapy could have saved her life, and why more people need to share

    UpdatesAMRPhage therapy
  12. UpdatesMay 12, 2023

    Phables is a new method to resolve phage genomes from fragmented viral metagenomic assemblies. This article by Vijini Mallawa

    Phables is a new method to resolve phage genomes from fragmented viral metagenomic assemblies. This article by Vijini Mallawaarachchi and colleagues shows how Phables identifies phage-like components, models each component, and identifies g

    UpdatesBioinformatic toolPhage genomics
  13. UpdatesMay 12, 2023

    This paper by Samuel Barnett and Daniel Buckley explores the role of soil viruses in the carbon cycle. They added 13C-labelle

    This paper by Samuel Barnett and Daniel Buckley explores the role of soil viruses in the carbon cycle. They added 13C-labelled carbon sources to soil and used metagenomic-SIP to detect 13C assimilation by viruses and their putative hosts. T

    UpdatesMicrobial community dynamicsResearch paperSoil viruses
  14. UpdatesMay 12, 2023

    A new ISME Journal article by Xiang Tang and colleagues shows lysogenic phages with arsM-bearing markers help bacterial commu

    A new ISME Journal article by Xiang Tang and colleagues shows lysogenic phages with arsM-bearing markers help bacterial communities adapt to trivalent arsenic toxicity. The phage-host interaction enabled the quick spread of arsM among soil

    UpdatesArsenic resistanceMicrobial adaptationResearch paperLysogeny
  15. UpdatesMay 12, 2023

    Pulmonary infections caused by Mycobacterium abscessus have been increasing. This study by Mylene Gorzynski and colleagues de

    Pulmonary infections caused by Mycobacterium abscessus have been increasing. This study by Mylene Gorzynski and colleagues deepens our understanding of phage–mycobacteria interaction mechanisms and identifies therapeutic phages that can low

    UpdatesPhage-host InteractionsResearch paperMycobacterium
  16. UpdatesMay 11, 2023

    Cryo-EM structure of the f1 filamentous phage, including its tips

    Nature Communications paper using cryo-electron microscopy of short Ff-derived nanorods to determine a structure of a filamentous virus (f1, fd or M13 phages) including the tips. Combined with mutagenesis, it identifies phage domains import

    UpdatesPapersPhage Biology
  17. UpdatesMay 5, 2023

    The Phage Therapy Today podcast interviewed Johan Wikstroem, the CEO of tolka.ai, about his story in transitioning from tech

    The Phage Therapy Today podcast interviewed Johan Wikstroem, the CEO of tolka.ai, about his story in transitioning from tech to biotech and founding a phage therapy company with the goal of treating his own M. abscessus infection and helpin

    UpdatesCommunityPhage therapyPodcast
  18. UpdatesMay 5, 2023

    Kids Research (part of Sydney Children's Hospitals Network) is hosting a webinar on May 19, 2023 at 2:00 PM AEST on phage the

    Kids Research (part of Sydney Children's Hospitals Network) is hosting a webinar on May 19, 2023 at 2:00 PM AEST on phage therapy entitled "Phage Therapy in Australia: STAMPing out problematic infections". The webinar will be presented by P

    UpdatesCommunityClinical TrialWebinarPhage therapy
  19. UpdatesMay 5, 2023

    From Sabrina Green via Twitter: Check out this documentary on #phage therapy in Belgium and Portugal. It is in Portuguese but

    From Sabrina Green via Twitter: Check out this documentary on #phage therapy in Belgium and Portugal. It is in Portuguese but interviews mostly in English.

    UpdatesCommunityDocumentaryPhage therapy
  20. UpdatesMay 5, 2023

    The 2023 Symposium on New Concepts in Prokaryotic Virus-host Interactions (October 2-4, 2023) will bring together researchers

    The 2023 Symposium on New Concepts in Prokaryotic Virus-host Interactions (October 2-4, 2023) will bring together researchers studying new concepts and mechanisms in phage biology, with topics including viral cell biology, anti-viral defens

    UpdatesCommunityPhage biologySymposium
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