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In this paper, Charles Dulberger and colleagues use live-cell fluorescence microscopy to visualize the spatiotemporal dynamics of mycobacteriophage infection in single cells and populations, showing that infection is dependent on the host n

Justin M. Jenson et al. published a new paper in Nature entitled Ubiquitin-like Conjugation by Bacterial cGAS Enhances Anti-phage Defence. In the paper, the authors show that Cap2 forms a thioester bond with the C-terminal glycine of cGAS a

In this issue of Cell, Brianna Duncan-Lowey et al. and Yina Gao et al. both show RADAR proteins assemble into massive molecular complexes but present distinct views about how these assemblies obstruct phage.

From the Phagebiotics Research Foundation: Greetings Phage friends! The 25th biennial International Evergreen Phage Meeting is set to kick off in person, in full Evergreen fashion, with Dr. Betty Kutter at the Evergreen State College. Mar

Our @PhageFiles podcast is finally here! Tune in on Spotify, Google Podcasts, Deezer and Amazon Music to listen to our first episodes. In our podcast we will discuss all things phage. You will hear from researchers and entrepreneurs interes

Armata Pharmaceuticals announces positive topline data from the completed Phase 1b2a SWARM-P.a. trial evaluating AP-PA02, a novel, inhaled multi-phage therapeutic for the treatment of chronic pulmonary Pseudomonas aeruginosa infections in c

Boston-based global health startup PhagePro has obtained an exclusive license to develop and market their phage cocktail product to prevent community spread of cholera.

A new Transplant Infectious Diseases study by Ghady Haidar (University of Pittsburgh School of Medicine) and colleagues reports the use of nebulized phage therapy to treat Burkholderia multivorans in a CF patient. Unfortunately this was a c

Amit Rimon (Hebrew University of Jerusalem) and colleagues published a new paper in Nature Communications on topical phage therapy in a mouse model of Cutibacterium acnes-induced lesions. They found that phage therapy may be a promising str

Cyanophages play an important role in controlling the abundance of their hosts, which are globally significant populations of Prochlorococcus and Synechococcus. In a new paper published in Viruses, Emily Dart (Clark University) and colleaug

Join the Webinar organized by Africa Phage Forum on ''grant writing and effective communication'' today from 4 PM West Central Africa Time (GMT+1). Our speaker is Dr. Tobi Nagel, founder and President of Phages for Global Health. Register h

A bioRxiv preprint reports that highly purified phage T4 was rapidly internalized in vitro by A549 lung epithelial cells, MDCK-I kidney cells and mouse bone marrow-derived macrophages without activating TLR9 or cGAS-STING inflammatory pathw

The Africa Phage Forum will be hosting a webinar on this Wednesday, 15th March 2023 at 6:00 PM East Africa Time (EAT). The webinar, titled ‘Scientific Writing & Effective Grant Writing’, will be given by Dr. Tobi Nagel, the Founder and Pres

The Good Virus is a new book by Tom Ireland that tells the story of phage research, from its beginnings to the present day. Now available for preorder in the UK and the US!

From Phage Twitter, via @hayleyn0rdstr0m: Adaptive Phage Therapeutics laid off 30% of the company this morning, including me… So, looking for phage research jobs in the DC metro area again! Drop me a DM if you have leads or want to chat.

The documentary, Salt in My Soul, follows the life of Mallory Smith, who was diagnosed with cystic fibrosis at age 3, and a resistant infection at age 15. In her final days, her father attempted to arrange phage therapy for her, but it was

In this study, Benjamin A. Adler (University of California, Berkeley) and colleagues used a high-throughput genetic screen to uncover genome-wide host suppressors of diverse single-gene lysis proteins (Sgls). See also this interview with th

Screen Australia has announced $4.6 million in production funding for 21 documentaries, including A Forgotten Cure (working title), a 54-minute phage therapy documentary that follows teams of scientists in Melbourne and Sydney (part of Phag

A new paper in Nature Microbiology by Madison C. Williams (University of Washington) and colleagues entitled Restriction endonuclease cleavage of phage DNA enables resuscitation from Cas13-induced bacterial dormancy reports that restriction

In a new preprint, Enea Maffei (University of Basel) and colleagues describe a new phage, Paride, which is able to kill dormant, antibiotic-tolerant bacteria. They suggest that this phage hijacks weak spots in the dormant physiology of anti