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The 2026 INPHARED snapshot contained 28,777 complete phage genomes, about twice the 2021 collection, but novel species-level diversity did not rise proportionally and host bias persisted. bioRxiv

The study re-engineered E. coli phage P2 tail fibers with S16 components. The resulting phages were detargeted from native LPS and could infect through S16’s protein receptor, OmpC. PubMed Central

Review of bacteriophage electron microscopy by H.-W. Ackermann (Advances in Virus Research, 2012). It argues that the quality of phage TEM micrographs has slipped since the 1970s, citing a survey of about 130 phage papers since 2006 in whic

PhageBench contains 5,600 samples across phage screening, quality control and phenotype annotation tasks. Its evaluation found stronger-than-random performance on some tasks and limitations in complex sequence reasoning. ACL Anthology

This review surveys machine-learning applications in bacteriophage research, including phage genomics, host interactions, and microbial-community analysis. Application of machine learning in bacteriophage research

The authors benchmarked ten phage identification tools using artificial contigs, a four-phage mock community, and simulated viromes. DeepVirFinder had the highest F1-scores on the artificial contigs and mock community (0.98 and 0.61); most

This review traces phage research from Frederick Twort’s 1915 observations through the discoveries that shaped modern biology. PubMed Central

This review describes clinical laboratory barriers to phage therapy in the United States, including inconsistent susceptibility testing and selection, a lack of phage–antibiotic synergy testing, and limited standard methods for testing phag

The paper introduces PhageDPO, a machine-learning tool available in Galaxy for identifying depolymerases in phage and prophage genomes. The authors say the source code is on GitHub. Computers in Biology and Medicine article

The recombinant PRA33gp45 hydrolysed K27 capsule polysaccharides and inhibited biofilm formation, disrupted mature biofilms, and altered biofilm architecture. In a Galleria mellonella larvae model, PRA33gp45 treatment lowered morbidity and

Broad Institute researchers used phage-assisted evolution to improve the editing efficiency of compact reverse transcriptases by up to 22-fold and generated prime editors 516-810 base pairs smaller than PEmax. The resulting PE6a-g editors e

npj Viruses is inviting submissions to its collection “Phages as antimicrobial therapy”, edited by Ruby CY Lin (The University of Sydney), Sabrina Green (KU Leuven) and Renee Ng (The Kids Research Institute Australia and The University of W