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Using the Klebsiella podophages KP32, K11 and KP34, the authors validated the interaction between the primary RBP branching domain and the secondary RBP docking peptide. They used this interaction to engineer a KP32 scaffold that propagated

Clara Torres-Barceló (University of Montpellier) and colleagues introduce the Phylogenetic Host-Range Index (PHRI) — a new metric to classify phages as specialists or generalists based on bacterial genetic diversity. Using phages infecting

Afif Jati (Monash University) and colleagues published a new paper in npj Viruses on how highly stable phages PIN1 and PIN2 have hallmarks of flagellotropic phages but infect immotile bacteria.

Taylor Andrews (Rutgers University) and colleagues published a new paper on re-expansion of host range in RNA phage phi6, showing specialized phi6 strains readily regained broader host ranges through both reversion and compensatory mutation

University of Alabama at Birmingham, USA is hiring a Researcher to investigate phage host range, genetic mobilization, and antibiotic resistance in staphylococci and streptococci, involving microbial genetics, biochemistry, and structural b

In a new paper in Cell Reports, Beatriz Beamud (Universidad Complutense de Madrid) and colleagues report on their study of the genetic determinants of host tropism in Klebsiella phages. They isolated 46 phages to challenge 138 representativ

PhD project to develop and test an approach to quickly generate phage variants with expanded host range.

Paper: The genetic basis of phage susceptibility, cross-resistance and host-range in Salmonella.

Paper: Multi-species host range of staphylococcal phages isolated from wastewater

Maria Loose (Justus-Liebig University Giessen, Germany) and colleagues published a new paper in Antibiotics showing natural bred ε2-phages have improved host range and virulence against uropathogenic Escherichia coli over their ancestor pha

Carlos Martinez-Soto (Guelph Research and Development Centre, Canada) and colleagues published a new paper in Viruses describing PHIDA: a high throughput turbidimetric data analytic tool to compare host range profiles of phages isolated usi

Lyman Ngiam (University of Queensland) and colleagues published a paper in Environmental Microbiology showing that phages isolated from non-target bacteria demonstrate broad host range infectivity against multidrug-resistant bacteria.

Anders Nørgaard Sørensen (University of Copenhagen) and colleagues published a new paper in Computational and Structural Biotechnology Journal showing subtypes of tail spike proteins predicts the host range of Ackermannviridae phages.

Karen Fong (Summerland Research and Development Centre, Canada) and colleagues published a review article in PHAGE on the host range of phages and its impact on the agri-food sector. They discuss the research pro

We know a lot about how phages expand their host ranges, but not so much about how they shrink them. A new Scientific Reports paper by Tzvi Holtzman (Israel Institute for Biological Research) and colleagues shows how T7 phage limits futile

We know a lot about how phages expand their host ranges, but not so much about how they shrink them. A new Scientific Reports paper by Tzvi Holtzman (Israel Institute for Biological Research) and colleagues shows how T7 phage limits futile