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Li Yuping (University of California, San Francisco) and colleagues published a new paper on a bacterial immune system targeting jumbo phages, showing it disrupts an early phage infection compartment to block replication.

Kate Harding (University of Otago) and colleagues published a new paper on genome-wide identification of bacterial genes for nucleus-forming phage infection, showing flagella and lipopolysaccharide biosynthesis genes are major contributors

Deepto Mozumdar (UCSF) and colleagues show that jumbo phage ΦKZ assembles a lipid vesicle upon infection. This early phage infection (EPI) vesicle contains phage proteins, DNA, host lipids, and membrane proteins. It protects the phage genom

Ana Georgina Cobián Güemes (University of California San Diego) and colleagues discovered that jumbo phages are effective against extensively drug-resistant (XDR) Pseudomonas aeruginosa infections in contaminated preservative-free eyedrops.

Ghent University, Belgium is hiring a PhD Student to study the tail fibers of Klebsiella jumbo viruses as a part of a four-year WEAVE project between Belgium (Ghent University, Prof. Yves Briers) and Poland (University of Wroclaw, Prof. Zuz

Eray Enustun (UCSD) and colleagues have used proximity labeling and localization mapping to systematically map out the protein interaction network of the ‘phage nucleus’ made by jumbo phages.

Researchers from UC San Diego, the J. Craig Venter Institute and Yale University have been awarded $10 million by the Howard Hughes Medical Institute (HHMI) to support research on using jumbo viruses as new therapeutic agents.