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Emily Armbruster (University of California San Diego) and colleagues published a new paper on sequential membrane- and protein-bound organelles in phage infection, showing chimalliviruses use two organelles - an early membrane-bound vesicle

Deepto Mozumdar (UCSF) and colleagues show that jumbo phage ΦKZ assembles a lipid vesicle upon infection. This early phage infection (EPI) vesicle contains phage proteins, DNA, host lipids, and membrane proteins. It protects the phage genom

Claire Kokontis (UC San Francisco) and colleagues have discovered the importance of conserved jumbo phage factors for protein import into a phage nucleus.

Eray Enustun (UCSD) and colleagues have used proximity labeling and localization mapping to systematically map out the protein interaction network of the ‘phage nucleus’ made by jumbo phages.

In the arms race between bacteria and phages, some large-genome jumbo phages have evolved a protein shell that encloses their replicating genome. In a new preprint, Eray Enustun and colleagues have used proximity labeling to identify a ‘pha