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Chase Morgan (University of California San Diego), Haley Atkins (Loyola University Chicago) and colleagues published a new review on phage therapy for urinary tract infections, showing phage therapy for this indication is promising, but nee

Adams and colleagues report in Nature Microbiology that the two genetic signatures defining the West African–South American (WASA) lineage of Vibrio cholerae, responsible for the 1991-2001 Latin American cholera epidemic, encode multiple an

She et al. retrieved 5,178 viral sequences encoding 12 Salmonella enterica virulence genes from the IMG/VR database and compared them with 466,136 S. enterica genomes from EnteroBase. Virulence genes including iacP, mgtB, misL and fliC were

You’re invited to submit an abstract to the inaugural Conference on Bacteriophages: Biology, Dynamics, and Therapeutics, chaired by Graham Hatfull (University of Pittsburgh) and Robert (Chip) Schooley (UCSD). Topics range from phage struct

W. Borges (Yale University) and colleagues published a new abstract on personalized phage therapy for cystic fibrosis, showing an LPS-5 and TIVP-H6 phage cocktail decreased P. aeruginosa biofilm formation and reduced IL-6 secretion for 15 d

Monyque Karoline de Paula Silva (Brazilian Center for Research in Energy and Materials) and colleagues published a new paper on deep learning in phage discovery, showing how AI enhances phage research through improved vMAG reconstruction, h

Robert Brzozowski, Amelia Schmidt (University of Montana) and colleagues published a new paper on prophage-encoded sRNA limiting lytic phage infection, showing a lambdoid prophage in adherent-invasive E. coli encodes an sRNA that downregula

Jyot Antani (Yale University) and colleagues published a new paper on evolutionary responses of E. coli to flagellotropic phage, showing bacteria evolved resistance through flagellar mutations while retaining motility, with some strains exh

Xiaolin Hou (Chinese Academy of Sciences) and colleagues published a new paper on advances in engineered phages for disease treatment, showing recent progress in enhancing phage targeting, stability, and synergistic combinations, across ant

You’re invited to submit an abstract to the inaugural Conference on Bacteriophages: Biology, Dynamics, and Therapeutics, chaired by Graham Hatfull (University of Pittsburgh) and Robert (Chip) Schooley (UCSD). Topics range from phage struct

Alexander Perfilyev (University of Copenhagen) and colleagues published a new preprint on discovering lytic phages in bacterial genomes, showing over 100,000 complete lytic phage genomes in bacterial assemblies, challenging assumptions and

Fernando Gordillo Altamirano (Monash University) and colleagues published a new paper on phage therapy failure mechanisms, showing pre-existing anti-prophage antibodies and bacterial heteroresistance contributed to treatment failure in a pa

Sarah Macdowell (The Ohio State University) and colleagues published a new paper on meropenem interactions with P. aeruginosa phages. They found that phages PEV2 and ΦKMV reduce bacterial burden in vitro and ex vivo, with enhanced efficacy

Alexandre Boulay (Ghent University) and colleagues published a new paper on segmentation of phage endolysin domains, showing SPAED achieves higher accuracy than existing tools by using AlphaFold's predicted aligned error matrix for hierarch

Seyoung Ko (Ulsan National Institute of Science and Technology, Korea) and colleagues published a new paper on deep learning-guided structural analysis of phage KPP105. Structural similarity analysis showed how its receptor binding protein

You’re invited to submit an abstract to the inaugural Conference on Bacteriophages: Biology, Dynamics, and Therapeutics, chaired by Graham Hatfull (University of Pittsburgh) and Robert (Chip) Schooley (UCSD). Topics range from phage struct

In Episode 45 of the International Antiviral Society (IAS-USA)’s Going anti-Viral podcast, Dr. Michael Saag speaks with Dr. Graham F. Hatfull (University of Pittsburgh) about Bacteriophages for the Treatment of Antimicrobial-resistant Bacte

Benjamin Chan (Yale University) and colleagues published a new paper on outcomes from the first 9 adult CF compassionate use cases treated with personalized inhaled P. aeruginosa phage therapy at Yale. 5-18 days after phage therapy, they sa

Emily Armbruster (University of California San Diego) and colleagues published a new paper on sequential membrane- and protein-bound organelles in phage infection, showing chimalliviruses use two organelles - an early membrane-bound vesicle

Tao Yang (Zhejiang University) and colleagues published a new paper on tumor-homing phage nanofibers for targeted cancer therapy, showing phage-templated platinum nanozymes can enhance photodynamic therapy of breast tumors by alleviating hy