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Dragica Damnjanovic (UNSW Sydney) and colleagues published a paper in BMC Microbiology on phage genotyping using repetitive-PCR, a rapid and inexpensive method to preliminarily screen phage isolates prior to selecting them for future studie

Kristopher Kieft and colleagues (University of Wisconsin-Madison) published a new paper in Microbiome about VIBRANT, a new hybrid machine learning and protein similarity approach for automated recovery, annotation and curation of microbial

Rafael Gonzalez-Serrano (Universidad Miguel Hernández) and colleagues published a new paper in MSystems describing an Alteromonas-targeting phage representing a new marine myovirus genus. They also determined that this phage requires a tail

Taylor Miller-Ensminger (Loyola University, Chicago) and colleagues published a new paper in PLOS ONE introducing Lu-1, a novel Lactobacillus jensenii phage abundant in the urogenital tract.

Phage Directory It's almost time for PHAVES: Phage Directory Virtual Event Series! (The acronym was too good; how could we not?) Save the date for June 16 at 8 AM Pacific Time (GMT-7) (details to come). And we're keeping signups open on a

Got phage protocols, or wish you did? The community can probably help! Here's an example from Twitter: "Hey, I'm working on phages and need to extract phage dna for characterization. Would you recommend Zymo kit for extraction? If not, whi

Last month, Cellexus installed a Dual CellMaker system for FixedPhage, who will use this system to produce phages designed to protect flowers, so people can enjoy longer lasting bouquets. To find out how the CellMaker can improve your phage

Could phage therapy target bacterial meningitis? Christian Møller-Olsen (University of Warwick, UK) and colleagues have shown that phage K1F can infect E. coli within cerebral endothelial cells without eliciting an inflammatory response. Th

Hans Gerstmans (Ghent University, Belgium) and colleagues published a new paper in Science Advances on a VersaTile-driven platform for rapid hit-to-lead development of engineered lysins. Stay tuned; next week's feature article will be a beh

Jean-Paul Pirnay (Queen Astrid Military Hospital, Belgium) lays out a vision for what personalized phage therapy might look like in the year 2035. His vision coincidentally also happens to lay out much of Phage Directory’s own roadmap!

David Olivenza (Universidad de Sevilla, Spain) and colleagues published a new paper in Environmental Microbiology on a fascinating new epigenetic system that can detect a wide range of phages and identify the type of receptor they recognize

Shannon Slattery (University of Limerick, Ireland) and colleagues published a new paper in Scientific Reports describing the isolation of a Proteus mirabilis strain from wastewater harbouring an integrative conjugative element (ICE) contain

Ahmed Sofy (Al-Azhar University, Egypt) and colleagues published a new paper in Foods on their use of a polyvalent phage to successfully control coagulase-negative Staphylococcus strains (including biofilm dispersal) in a food setting.

Register for an upcoming virtual event on AMR and the requirement for a new business model for antimicrobials, hosted by members of European Parliament (June 4 at 12pm CET). Includes a talk by Jean-Paul Pirnay (Queen Astrid Military Hospita

Phage Directory We learned that the CURE project partner from Sweden, which we wrote about in last week's Capsid & Tail article, "Could phages cure asthma?", is no longer part of the CURE team. Thanks very much to Sofia Romagosa at the Euro

Vitalis Phage Therapy In the 4th ed. of #AllAboutPhageTherapy we're honored to have Dr Elizabeth 'Betty' Kutter live in discussion. Lovingly referred to as “The First Lady of #PhageResearch”, Betty is one of the most experienced & respected

Alita Burmeister (Yale University) and colleagues published a new paper in PNAS describing how pleiotropy complicates trade-offs between phage resistance and antibiotic resistance for a bacterial host, which has implications for phage thera

Anti-CRISPRs are widespread among phages, but it's been hard to screen for them. Jiawei Wang and colleagues at Monash University have developed an ensemble learning based predictor, PaCRISPR, to accurately identify anti-CRISPRs from protein

Check out how the US Army's Combat Capabilities Development Command (CCDC) Chemical Biological Center is making use of a polymerized phage in biomanufacturing of BioCNFs, a black carbon material like charcoal that can help break up mustard

Register for an upcoming virtual event on AMR and the requirement for a new business model for antimicrobials, hosted by members of European Parliament (June 4 at 12pm CET). Includes a talk by Jean-Paul Pirnay (Queen Astrid Military Hospita