Search

You’re invited to submit an abstract to the inaugural Conference on Bacteriophages: Biology, Dynamics, and Therapeutics, chaired by Graham Hatfull (University of Pittsburgh) and Robert (Chip) Schooley (UCSD). Topics range from phage struct

W. Borges (Yale University) and colleagues published a new abstract on personalized phage therapy for cystic fibrosis, showing an LPS-5 and TIVP-H6 phage cocktail decreased P. aeruginosa biofilm formation and reduced IL-6 secretion for 15 d

Monyque Karoline de Paula Silva (Brazilian Center for Research in Energy and Materials) and colleagues published a new paper on deep learning in phage discovery, showing how AI enhances phage research through improved vMAG reconstruction, h

Robert Brzozowski, Amelia Schmidt (University of Montana) and colleagues published a new paper on prophage-encoded sRNA limiting lytic phage infection, showing a lambdoid prophage in adherent-invasive E. coli encodes an sRNA that downregula

Jyot Antani (Yale University) and colleagues published a new paper on evolutionary responses of E. coli to flagellotropic phage, showing bacteria evolved resistance through flagellar mutations while retaining motility, with some strains exh

Xiaolin Hou (Chinese Academy of Sciences) and colleagues published a new paper on advances in engineered phages for disease treatment, showing recent progress in enhancing phage targeting, stability, and synergistic combinations, across ant

"This feels just like the early days of the HIV crisis. People are dying, you're not hearing about it. We need a group like ACT UP to bring this to the public. We're not going to get phage therapy until people start demanding we have it." "

You’re invited to submit an abstract to the inaugural Conference on Bacteriophages: Biology, Dynamics, and Therapeutics, chaired by Graham Hatfull (University of Pittsburgh) and Robert (Chip) Schooley (UCSD). Topics range from phage struct

Alexander Perfilyev (University of Copenhagen) and colleagues published a new preprint on discovering lytic phages in bacterial genomes, showing over 100,000 complete lytic phage genomes in bacterial assemblies, challenging assumptions and

Fernando Gordillo Altamirano (Monash University) and colleagues published a new paper on phage therapy failure mechanisms, showing pre-existing anti-prophage antibodies and bacterial heteroresistance contributed to treatment failure in a pa

Sarah Macdowell (The Ohio State University) and colleagues published a new paper on meropenem interactions with P. aeruginosa phages. They found that phages PEV2 and ΦKMV reduce bacterial burden in vitro and ex vivo, with enhanced efficacy

Alexandre Boulay (Ghent University) and colleagues published a new paper on segmentation of phage endolysin domains, showing SPAED achieves higher accuracy than existing tools by using AlphaFold's predicted aligned error matrix for hierarch

Seyoung Ko (Ulsan National Institute of Science and Technology, Korea) and colleagues published a new paper on deep learning-guided structural analysis of phage KPP105. Structural similarity analysis showed how its receptor binding protein

"This feels just like the early days of the HIV crisis. People are dying, you're not hearing about it. We need a group like ACT UP to bring this to the public. We're not going to get phage therapy until people start demanding we have it." O

Researchers at the Center for Phage Biology and Therapy at Yale report in Nature Medicine on nine adults with cystic fibrosis treated by nebulization with phages selected to kill infecting bacteria and also weaken the survivors, making them

Research Tech: Phage Genetics in Drosophila at Penn State, The Bordenstein Lab in State College, PA The Bordenstein Laboratory in Penn State University’s One Health Microbiome Center seeks two Research Technologist - Life Sciences (Advanc

Research Tech: Phage Genetics in Drosophila at Penn State, The Bordenstein Lab in State College, PA The Bordenstein Laboratory in Penn State University’s One Health Microbiome Center seeks two Research Technologist - Life Sciences (Advanc

Research Tech: Phage Genetics in Drosophila at Penn State, The Bordenstein Lab in State College, PA The Bordenstein Laboratory in Penn State University’s One Health Microbiome Center seeks two Research Technologist - Life Sciences (Advanc

"We put a dent in the theory that phage therapy doesn't work. Maybe it does work. Maybe it's worth taking a risk." This week we talk to Jonathan Solomon, CEO of BiomX, about their successful phase 2 clinical trial for diabetic foot osteomye

Manifold Bio in Boston, MA is hiring a Scientist, Phage Display & Discovery, to study phage display techniques and develop novel discovery platforms for therapeutic proteins and antibodies.`