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An anonymous donation to the University of Toronto has led to a grant call of up to 1.5 million Canadian dollars for phage therapy research, with letters of interest due on April 19th. There are options for $200,000 and $50,000 allocations.

For 6 decades, it has been a mystery how ssDNA phages use their ‘maturation’ (Mat) protein (1 of 4 proteins encoded by the phage, known to be involved in plus recognition) to enter the host cell. Jirapat Thongchol (Texas A&M University) and

Maik Wolfram-Schauerte (Max Planck Institute for Terrestrial Microbiology) and colleagues published a preprint revealing that T4 phage RNA is NAD-capped, and alters the NAD-cap epitranscriptome of E. coli during infection through a phage-en

Siva Uppalapati (University of Colorado School of Medicine) and colleagues discovered that a Salmonella prophage terminase is redox sensitive — it unexpectedly switches into acting as a tRNAse under oxidative stress, arresting host translat

A human oral Saccharibacteria isolate (TM7x) protected its host Schaalia odontolytica XH001 from lytic phage LC001 during surface-associated growth, with down-regulation of a cell-wall polysaccharide gene cluster that affects phage binding.

WHO Europe in collaboration with the Global AMR R&D Hub is hosting a webinar called ‘Towards building the evidence for broader use of bacteriophages from an AMR One Health perspective’ on April 18. This 1st webinar in a series of 3 will foc

IDWeek 2024 (Oct 16-19, Los Angeles) is now accepting applications for their Pipeline Sessions and BugHub Stages, inviting companies and researchers to submit novel antimicrobial agents or diagnostic technologies for a chance to present at

The LuxO-OpaR quorum-sensing cascade differentially controls Vibriophage VP882 lysis-lysogeny decision making in liquid and on surfaces, according to a new preprint by Francis Santoriello and Bonnie Bassler at Princeton University.

Phages avoid autoimmunity from cognate immune systems as an intrinsic part of their life cycles, according to a new paper by Jakob Rostøl (Imperial College London) and colleagues.

Phage banks are fragmented, and it’s time to unify them, according to a new review led by Gregory Resch (University of Lausanne) and including authors from Felix d’Herelle Center and DSMZ, two major phage repositories.

Phage-based technologies in the African AgriFood sector have major potential, according to a new report by Innovate UK as part of AgriFood Africa Connect.

Want a quick visual on global prevalence of Pseudomonas resistance to fluroquinolones? Or E. coli resistance to colistins? ResistanceMap is a new interactive visualization tool for looking at AMR around the world, created by One Health Trus

Aaryan Harshith (Stanford University) has just launched PhageBase, a dedicated phage TEM image database. There are already quite a few phages on there; feel free to upload your own! He wrote a blog introducing it here.

Phage researchers are invited to save the date for the 2024 International Soil Virus Conference in Livermore, California, USA, from June 25 to June 27, focusing on exploring the multifaceted roles of soil viruses within a One Health framewo

New phage textbook edition alert! Tristan Ferry, an ID physician in Lyon, announced the release of the second edition of "Bacteriophage Therapy; From Lab to Clinical Practice.". The book, edited by Sanna Sillankorva and Joana Azeredo, cover

NexaBiome (previously FixedPhage) has partnered with JAFRAL to ramp up development (a hundredfold increase!) of their industrial-scale production of immobilized phage. This is part of NexaBiome's strategy to expand deeper into the human hea

Danica Schmidtke (Stanford University) and colleagues published a new preprint on how the prototypic crAssphage demonstrates a phage-plasmid lifestyle, persisting extrachromosomally without integrating into the host’s chromosome.

Fan Yang (University of Texas, Tyler School of Medicine) and colleagues published a new paper on phage therapy for the treatment of M. tuberculosis infections in humanized mice. They saw that mice infected with aerosolized TB then treated w

Ruo Han Wang (City University of Hong Kong) and colleagues published a paper on PhageScope: a new online phage database with comprehensive annotations comprising 873,718 phage sequences. It provides annotations on genome completeness, host

Paul Turner (Yale University) and colleagues have written a new review on gaps in modern phage therapy R&D. It includes some fun exploration of how AI & synbio could ease phage therapy logistics, a walkthrough of how and why new funding & r