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M. J. N. Thomas (University of Manchester) and colleagues published a new paper in mSystems called ‘What makes a temperate phage an effective bacterial weapon?’. They combine mathematical models and experimental work to reveal how temperate

Could phages play a role in microbial adaptation to spaceflight conditions? Iris Irby and Jared Broddrick (NASA Ames Research Center) have shown that bacterial strains from the International Space Station show significant differences in pha

Catherine Hernandez (University of California, Berkeley) provides evidence supporting the role of coevolution in maintaining diversity among phages, revealing that coevolved phages have more mutations and greater congruence across populatio

Despite their unique biology and biotech potential, only a small number of plasmid-dependent phages have been characterized. Natalia Quinones-Olvera (Harvard Medical School) and colleagues published the results of their recent systematic se

Jun-Tao Zhang (Southern University of Science and Technology, China) colleagues have shown the structural basis for phage-mediated activation and repression of the anti-phage defense system DSR2. They use cryoEM to show how DSR2 interacts w

Bradley Schmitz (National University of Singapore) and colleagues have established criteria for identifying good surrogates for water reuse, including 11 viruses, 2 phages, and 3 bacteria.

Ryan Cook (Quadram Institute) and colleagues investigated the differences in viral populations recovered from human gut samples using Nanopore and Illumina sequencing technologies, finding that while Illumina is preferable for fully resolve

Anisha M. Thanki (University of Leicester) and colleagues found that broad host range phages can effectively target and clear Clostridium perfringens in poultry.

Claire Kokontis (UC San Francisco) and colleagues have discovered the importance of conserved jumbo phage factors for protein import into a phage nucleus.

Jirapat Thongchol (Texas A&M University) and colleagues have shown how Pseudomonas phage PP7 utilizes the type IV pilus (T4P) to enter host cells.

Mateusz Szymczak (University of Warsaw) and colleagues have developed an effective antibiofilm strategy using phages armed with silver nanoparticles.

Samuel Greenrod (University of Oxford) and colleagues explored the effects of warming on the interaction between the P. aeruginosa and three diverse lytic phages. They found that while temperatures up to 40°C had minimal impact, 42°C signif

Wei Liu and (Tsinghua University) and colleagues have shown that phage communities contribute to antibiotic resistance genes in sludge plants.

Siva Uppalapati (University of Colorado School of Medicine) and colleagues discovered that a Salmonella prophage terminase is redox sensitive — it unexpectedly switches into acting as a tRNAse under oxidative stress, arresting host translat

Phages avoid autoimmunity from cognate immune systems as an intrinsic part of their life cycles, according to a new paper by Jakob Rostøl (Imperial College London) and colleagues.

Danica Schmidtke (Stanford University) and colleagues published a new preprint on how the prototypic crAssphage demonstrates a phage-plasmid lifestyle, persisting extrachromosomally without integrating into the host’s chromosome.

Milan Gerovac (University of Würzburg) and colleagues published a new paper revealing how phage-encoded proteins, particularly from jumbo phage ΦKZ, target and co-opt P. aeruginosa ribosomes immediately after infection. They make the case t

Nicholas Smith (University at Buffalo) and colleagues published a new paper exploring the pharmacodynamics of three unique Pseudomonas phages by simulating different dosing strategies (cocktails vs. single phage, bolus vs. prolonged dosing)

Ana Rita Costa (Delft University of Technology) and colleagues published a new paper showing that clinical P. aeruginosa strains accumulate phage defense systems (some have at least 19!), that many individual defense systems target specific

Cristina Leal Rodríguez (Copenhagen University Hospital) and colleagues published a new paper on how the infant gut virome is associated with preschool asthma risk independently of bacteria.