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Nils Birkholz (University of Otago) and colleagues investigated the dual regulatory mechanisms of the Aca2 protein, showing that it represses anti-CRISPR gene expression by binding both DNA and RNA.

Chantel Trost (University of Toronto) and colleagues found that the anti-CRISPR protein AcrIF25 disrupts the type I-F CRISPR-Cas system by pulling apart Cas7 from its guide RNA, one subunit at a time. (And it does this with no apparent enzy

Paper: AcaFinder: genome mining for anti-CRISPR associated genes

Paper: Anti-CRISPR prediction using deep learning reveals an inhibitor of Cas13b nucleases.

Paper: A truncated anti-CRISPR protein prevents spacer acquisition but not interference

Xu Peng (University of Copenhagen, Denmark) is looking for a postdoc to work on CRISPR and anti-CRISPR of phages and archaeal viruses. Interested candidates may email the PI at peng@bio.ku.dk or DM her on Twitter (@XuPeng01770032).

Yuping Li and Joseph Bondy-Denomy (University of California San Francisco) published a new review in Cell Host & Microbe discussing how anti-CRISPRs affect the ecology and evolution of bacteria and phage.

Kevin Forsberg (Fred Hutchinson Cancer Research Center) and colleagues have published a new paper in eLife on a high-throughput method to find new phage-encoded anti-CRISPR proteins. The method involves expressing gene fragments from human

Kevin Forsberg (Fred Hutchinson Cancer Research Center) and colleagues have published a new paper in eLife on a high-throughput method to find new phage-encoded anti-CRISPR proteins. The method involves expressing gene fragments from human

Stineke Van Houte, Cornwall, UK CRISPR immunity protects bacteria against bacteriophage infections. Recent work from our lab demonstrates that phages that encode anti-CRISPR proteins immunosuppress bacterial hosts, which allows other phages

Stineke Van Houte, Cornwall, UK CRISPR immunity protects bacteria against bacteriophage infections. Recent work from our lab demonstrates that phages that encode anti-CRISPR proteins immunosuppress bacterial hosts, which allows other phages