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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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231 news items

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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesApr 11, 2025

    Giuseppina Mariano, Justin Deme (University of Glasgow & National Cancer Institute) and colleagues published a new paper on s

    Giuseppina Mariano, Justin Deme (University of Glasgow & National Cancer Institute) and colleagues published a new paper on structural and mechanistic insights into Zorya phage defense systems, showing ZorAB forms an ion-driven motor comple

    UpdatesResearch paperPhage defense
  2. UpdatesApr 11, 2025

    Nanami Kubota (University of Pittsburgh) and colleagues published a new preprint on filamentous phage exploitation of bacteri

    Nanami Kubota (University of Pittsburgh) and colleagues published a new preprint on filamentous phage exploitation of bacteria, showing that mutant Pf phages can drive P. aeruginosa populations to lower fitness through superinfection and mi

    UpdatesPreprintPf phageFilamentous phages
  3. UpdatesApr 5, 2025

    Review of bacteriophage therapy in freshwater and saltwater aquaculture species (MDPI)

    A review of recent advances in using bacteriophages to treat the most common bacterial infectious diseases of cultured fish, shellfish and crustaceans. It concludes that the documented research supports phage therapy in aquaculture but that

    UpdatesPapersReviewAquaculture
  4. UpdatesApr 4, 2025

    Dear Phage Protein enthusiast, We are pleased to invite you to The Phage Protein Meeting, September 10-11, 2025 in Ghent, Be

    Dear Phage Protein enthusiast, We are pleased to invite you to The Phage Protein Meeting, September 10-11, 2025 in Ghent, Belgium. The Phage Protein Meeting is an interdisciplinary conference organized by academics and dedicated to advanc

    UpdatesCommunityConferencePhage proteins
  5. UpdatesApr 4, 2025

    Huge milestone alert! BiomX has announced successful Phase II clinical trial results for their BX211 phage product against di

    Huge milestone alert! BiomX has announced successful Phase II clinical trial results for their BX211 phage product against diabetic foot osteomyelitis! Subscribe to the Podovirus podcast to learn more — we'll be interviewing BiomX CEO Jona

    UpdatesClinical trialsPhage therapyBiotech news
  6. UpdatesApr 4, 2025

    Marian Dominguez-Mirazo (Georgia Institute of Technology) and colleagues published a new preprint on inferring phage trait he

    Marian Dominguez-Mirazo (Georgia Institute of Technology) and colleagues published a new preprint on inferring phage trait heterogeneity from population data, showing latent period variation in cyanophages exceeds that of coliphages and bur

    UpdatesPhage ecologyPreprint
  7. UpdatesApr 4, 2025

    Jason Wilson (University of Sheffield) and colleagues published a new paper on structural analysis of a phage that penetrates

    Jason Wilson (University of Sheffield) and colleagues published a new paper on structural analysis of a phage that penetrates bacterial S-layers, showing the phage has an unusually long tail that contracts less than other phages, likely ena

    UpdatesResearch paperS-layerStructural biology
  8. UpdatesApr 4, 2025

    Isabella Romano (University of New Mexico) and colleagues published a new paper on RNA phage-derived vaccines against heroin

    Isabella Romano (University of New Mexico) and colleagues published a new paper on RNA phage-derived vaccines against heroin and fentanyl, showing the vaccines elicit high-titer antibodies and protect against opioid-induced effects in mice

    UpdatesResearch paperPhage vaccines
  9. UpdatesApr 4, 2025

    José Penadés (Imperial College London) and colleagues published a new review on phage satellite genetics, ecology and evoluti

    José Penadés (Imperial College London) and colleagues published a new review on phage satellite genetics, ecology and evolution, diving into how these elements impact bacterial evolution and virulence.

    UpdatesPhage satellitesCoevolutionReview
  10. UpdatesMar 31, 2025

    Phage therapy against drug-resistant Klebsiella

    This review surveys lytic bacteriophages and related approaches being studied against antibiotic-resistant Klebsiella pneumoniae. Bacteriophage therapy: a possible alternative therapy against antibiotic-resistant strains of Klebsiella pneum

    UpdatesPapers
  11. UpdatesMar 31, 2025

    Jumbo phages use a membrane-bound EPI vesicle and then the phage nucleus to compartmentalize their genomes (Cell Host & Microbe)

    Bacteriophages of the Chimalliviridae family are shown to use two successive compartments during infection: a membrane-bound early phage infection (EPI) vesicle that encloses the injected genome and expresses early genes, and the protein-la

    UpdatesPapersPhage Biology
  12. UpdatesMar 28, 2025

    Dear Phage Protein enthusiast, We are pleased to invite you to The Phage Protein Meeting, September 10-11, 2025 in Ghent, Be

    Dear Phage Protein enthusiast, We are pleased to invite you to The Phage Protein Meeting, September 10-11, 2025 in Ghent, Belgium. The Phage Protein Meeting is an interdisciplinary conference organized by academics and dedicated to advanc

    UpdatesCommunityConferencePhage proteins
  13. UpdatesMar 28, 2025

    Li Yuping (University of California, San Francisco) and colleagues published a new paper on a bacterial immune system targeti

    Li Yuping (University of California, San Francisco) and colleagues published a new paper on a bacterial immune system targeting jumbo phages, showing it disrupts an early phage infection compartment to block replication.

    UpdatesResearch paperJumbo phagesPhage-host interactions
  14. UpdatesMar 28, 2025

    Brittany Supina (University of Alberta) and colleagues published a new paper on isolation and characterization of a novel Bur

    Brittany Supina (University of Alberta) and colleagues published a new paper on isolation and characterization of a novel Burkholderia jumbo phage, showing it uses flagella as a receptor, controls rice seedling rot, and steers B. glumae tow

    UpdatesPhage-host interactionsJumbo phageResearch paper
  15. UpdatesMar 28, 2025

    Himanshu Batra (Catholic University of America) and colleagues published a new preprint on targeted phage T4-based nanopartic

    Himanshu Batra (Catholic University of America) and colleagues published a new preprint on targeted phage T4-based nanoparticles, showing these nanoparticles can reactivate latent HIV-1 in CD4+ T cells without causing global T cell activati

    UpdatesNanoparticlesHIVPreprint
  16. UpdatesMar 28, 2025

    Tamsin Redgwell (Copenhagen University Hospital) and colleagues published a new paper on prophage induction in infant gut mic

    Tamsin Redgwell (Copenhagen University Hospital) and colleagues published a new paper on prophage induction in infant gut microbiomes, showing most prophages were actively induced and may modulate host bacterial functionality through access

    UpdatesProphageGut viromeInfants
  17. UpdatesMar 28, 2025

    Arne Echterhof (Stanford University School of Medicine) and colleagues published a new preprint on modeling whole-body phage

    Arne Echterhof (Stanford University School of Medicine) and colleagues published a new preprint on modeling whole-body phage distribution in mice, using Physiologically-based Pharmacokinetic Modeling. They show rapid elimination of phage an

    UpdatesPharmacokineticsPreprint
  18. UpdatesMar 23, 2025

    Scalable purification of bacteriophage preparations with alkaline phosphatase and anion-exchange chromatography (Journal of Chromatography A)

    Saavedra, Silva-Santos, Duarte and Azevedo describe in Journal of Chromatography A a purification workflow for bacteriophage preparations built around anion-exchange chromatography, using phage T4 and E. coli K12 as models. Treating with al

    UpdatesPapersManufacturingPhage Biology
  19. UpdatesMar 21, 2025

    Yves Briers (Ghent University, Belgium) and colleagues are hosting The Phage Protein Meeting September 10-11, 2025. The even

    Yves Briers (Ghent University, Belgium) and colleagues are hosting The Phage Protein Meeting September 10-11, 2025. The event is for researchers working with phage proteins such as phage lysins, tail fibers, tailspikes, depolymerases, and

    UpdatesCommunityConferencePhage proteins
  20. UpdatesMar 21, 2025

    The Belgian Society for Viruses of Microbes (BSVoM) is hosting their 4th Annual Symposium on Phage Research, taking place on

    The Belgian Society for Viruses of Microbes (BSVoM) is hosting their 4th Annual Symposium on Phage Research, taking place on September 12, 2025 (the day after the Phage Protein Meeting, in the same city!). Particularly, there will be also

    UpdatesCommunityConferenceViruses of MicrobesPhage therapy
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