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Oliver Charity (Quadram Institute Bioscience) and colleagues published a new paper in Microbial Genomics on how increased phage resistance through lysogenic conversion accompanies emergence of a Salmonella Typhimurium pandemic strain.

In this preprint, the authors use microfluidic culture and high resolution microscopy to study how the cellular scale architecture of model 2-species biofilms impacts cell-cell and cell-phage interactions controlling larger scale population

In a new preprint, researchers from the University of Minnesota report on their efforts to catalog human gut phages using metagenome assembly and long-read sequencing.

In a new preprint, Medeea Popescu and colleagues report that the bacteriophage Pf4, produced by Pseudomonas aeruginosa, dampens inflammatory responses in response to either P. aeruginosa airway infection in a mouse model of acute pneumonia

In a new paper in Current Opinion in Microbiology, Aisylu Shaidullina and Alexander Harms present an overview of recent breakthroughs in the systematic investigation of phage-host interactions. They highlight recent work on the molecular ba

This preprint by Séraphine Degroux et al. presents the electron cryo-microscopy structure of bacteriophage T5 RBPpb5 in complex with its E. coli receptor, the iron ferrichrome transporter FhuA.

In a new paper in Nature Microbiology, Benjamin Adler et al. show that the CRISPR-Cas13a protein from Leptotrichia buccalis has robust antiviral activity against a wide range of phages and can be applied as a generalizable tool for editing

Guy Mason and Enrique R. Rojas published a new preprint entitled Mechanical compression induces persistent bacterial growth during bacteriophage predation. The paper discusses how bacteria can grow persistently when perfused with high-titer

Adi Millman et al. published a new paper in Cell Host & Microbe entitled An expanded arsenal of immune systems that protect bacteria from phages. They report the discovery of 21 defense systems that protect bacteria from phages, based on co

In a new paper in mBio, Eugen Pfeifer and colleagues report that phage-plasmids commonly encode different and multiple types of resistance genes of high clinical importance, often in integrons.

In a new paper in Microbiology Spectrum, Aude Ferran (Université de Toulouse) and colleagues report that the combination of phages and antibiotics can prevent the selection of resistant bacteria.

Brendan J. O’Hara (Tufts University School of Medicine) and colleagues published a paper in PLOS Genetics entitled The Vibrio cholerae Seventh Pandemic Islands act in tandem to defend against a circulating phage.

John M. Eppley (University of the West of England) and colleagues published a new paper in PNAS entitled Marine viral particles reveal an expansive repertoire of phage-parasitizing mobile elements. They found that marine phage satellites ar

Frank Oechslin and colleagues published a paper in PLOS Biology entitled Phage endolysins are adapted to specific hosts and are evolutionarily dynamic. Using CRISPR-Cas9 genome editing, the authors found that phage endolysins could adapt to

Fengjuan Tian et al. (IME Research Institute, China) published a new paper in Virus Research entitled Molecular dissection of the first Staphylococcus cohnii temperate phage IME1354_01.

In a new study published in Cell, researchers led by Eran Elinav (Weizmann Institute of Science) show that combination phage therapy can be used to target Klebsiella pneumoniae strains associated with inflammatory bowel disease.

Rima Fanaei Pirlar et al. published a new paper in Pharmaceutics, where they characterized a new phage, CUB19, which shows potent antimicrobial and antibiofilm activity against Stenotrophomonas maltophilia.

In a new paper in Cell Chemical Biology, Quirin Emslander and colleagues present a new cell-free platform for personalized production, transient engineering, and proteomic characterization of a broad spectrum of phages.

In a new paper published in Nature Ecology & Evolution, Martin Guillemet et al. study the effect of coevolving phage populations on the diversification of bacterial CRISPR immunity across space and time. They demonstrate that the negative-f

SpyPhage: A Cell-Free TXTL Platform for Rapid Engineering of Targeted Phage Therapies, by Sahan B. W. Liyanagedera and colleagues, proposes the SpyPhage system where a “scaffold” bacteriophage is engineered to incorporate a SpyTag moiety on