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Paper: Combination of pre-adapted bacteriophage therapy and antibiotics for treatment of fracture-related infection due to pandrug-resistant Klebsiella pneumoniae. — Anaïs Eskenazi et al

Paper: Lambda phage ‘counts’ the number of coinfecting viruses and then uses this to assess the abundance of potential hosts and decide whether to become dormant. This single-cell tool illuminates how! — Tianyou Yao et al.

Paper: Bacteriostatic antibiotics promote CRISPR-Cas adaptive immunity by enabling increased spacer acquisition — Tatiana Dimitriu et al

Preprint: Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion — Jeremy Garb et al.

Olivier Zablocki shares an updated ecosystem of microbiome/virome apps and guides (iVirus 2), which are freely available to run on CyVerse & DOE KBase. Learn more with their new perspective piece.

In an effort to help companies navigate the development of their bacteriophage product, IHMA’s VP Global Microbiology Services & CSO, Daniel Sahm has compiled a summary of key considerations to address prior to beginning clinical trials.

Thanks to all who came out to the first iVoM Season 2 event of 2022! Next: Feb 2 from 2-3 PM CET Topic: Phage application in the One Health approach. Speakers: Dr. Cath Rees, Prof. Mariana Piuri, Prof. Lone Brøndsted. If you want to join

IPATH invites the phage therapy community to the virtual screening and discussion event for the new documentary, Salt in My Soul. This film recounts the struggles and feelings of Mallory Smith, who lost her battle with cystic fibrosis and a

Phages for Global Health invites scientists from anywhere in Africa, whether or not you have previously attended our workshops, to fill out this survey about your ongoing phage work or any aspirations for future phage-related activities. P

Happy New Year from PHAGE Journal! To celebrate the new year, you can access the papers in PHAGE Journal's new "Special Issue on Phage Informatics and AI" for free for a limited time! Included in this issue: - Phage Genome Annotation: Whe

Not long left to submit abstracts to the virus & mobile genetic elements session at #AbSciCon22 (May 15-20 in Atlanta, GA). You can present in-person or virtually. Invited speaker Dr. Rachel Whitaker will discuss "Epidemics of Gene Flow in

I would like to introduce Phage Commander, a new genome annotation tool that runs a genome through multiple gene calling programs simultaneously and outputs the results to a single spreadsheet. Phage Commander includes the following program

Exodus is an open source tool for detection and quantification of phage pooled together in a single sample. It allows for accurate quantification of known phage, even when they are sequenced alongside with other very similar phages.

Preprint: Class I DISARM provides anti-phage and anti-conjugation activity by unmethylated DNA recognition.

Paper: Type I CRISPR-Cas provides robust immunity but incomplete attenuation of phage-induced cellular stress.

Preprint: a novel locally c-di-GMP-controlled exopolysaccharide synthase is required for phage N4 Infection of E. coli.

The CF Foundation has awarded $5 Million to BiomX to conduct a Phase 1b/2a clinical trial to test the safety and tolerability of phage therapy for Pseudomonas aeruginosa infections in people with cystic fibrosis.

New profile of Citizen Phage, a new UK-based citizen science project run by Ben Temperton. “In the first few months of operation, the Citizen Phage Library has isolated 78 new phages from around 100 samples”. (Phage Directory is excited to

Microbiome Times analysed its Microbiome Drug Database™, a repository of biotechs developing microbiome drugs, for phage-related drugs. They found that almost 70% of the total of 100 company-sponsored, phage-based drug development programs

Paper: Digital phagograms: predicting phage infectivity through a multilayer machine learning approach. See Dimi Boeckaerts’ Twitter thread for key points.