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"When I first treated, we had no idea how much to give, how often to give... we weren't aware of what the concentration of phage should be." IPATH's Dr. Saima Aslam shares how eight years of treating patients has taught her team to achieve

It’s Phage Picks time! This week, we highlight some new mind-expanding papers — one showing how phage killing might train the immune system like vaccines, one unpacking how temperate phages rewrite bacterial flagella with RNA-guided tools,

"We put a dent in the theory that phage therapy doesn't work. Maybe it does work. Maybe it's worth taking a risk." This week we talk to Jonathan Solomon, CEO of BiomX, about their successful phase 2 clinical trial for diabetic foot osteomye

What else can phages do, besides kill bacteria? Are bacteria even needed to make them anymore? In this month's Phage Picks issue, we cover phage+AAV hybrids to deliver genes to eukaryotic cells, cell-free phage synthesis, and a bonus must-t

A team of Hungarian scientists created a global ‘superbug map’ for Acinetobacter baumannii strains, paving the way for scalable phage therapy to combat antibiotic-resistant infections in hospitals. A team of Hungarian scientists created a g

This week, NYIT undergrad student Yamini Patel shares insights from Viruses of Microbes 2024 in Australia. She highlights what she learned, from phage therapy with Rob Lavigne, to Colin Hill's insights on crAssphage, to what's new in microb

What's it like treating patients with phages at a major US medical center? In a new Podovirus Podcast episode, Mayo Clinic's Dr. Gina Suh shares insights from 5 years of phage therapy — the successes, the challenges, and what it takes to ma

How can we harness phage-based technologies to edit bacterial genes in the microbiome? Jesus Fernandez of Eligo Biosciences shares how they're modifying phages to base-edit mouse gut bacteria, and how that opens up new possibilities for tre

This week we're featuring Michael Shamash's reflections on a couple of noteworthy topics covered at this year's Hanson Wade phage summit. Michael is a McGill University PhD student by day / awesome Phage Directory volunteer by night — thank

This week, we hear from Gabor Apjok, who has responded to many of our Phage Alerts. Working out of his lab in Hungary, he has successfully isolated and supplied phages that have gone on to treat several patients around the world. Most resea

Round up time! This month we did our first 'Phage Picks' issue, dove into how prophages impact fly sperm, shared insights and recordings from Urmi's webinar series with top phage therapy clinicians, and Elisabet More from PDB Biotech taught

This week, Prof. Urmi Bajpai shares insights (and recordings!) from a phage therapy clinician webinar series she hosted recently, which featured Gina Suh, Chip Schooley, Jon Iredell, Gopal Nath, and Mzia Kutadeladze. At the end of 2023, the

This week, we learn from David and Lorenzo from BioNTech (formerly PhagoMed) about their experience with phage inhibition of S. aureus phages by plasma and synovial fluid. Read our papers for more details: Saez et al., 2021; Mutti et al 202

This month we heard about the ICBRAR phage conference in India, got an excerpt from The Good Virus by Tom Ireland, had a look behind the scenes of a Swiss team battling UTIs with engineered phages, and learned about speeding up the phage th

This week, we have an amazing guest article from Matthew Dunne and the Loessner Lab at ETH Zurich about their phage-based diagnostic tool and engineered phage work. Recently, the phage engineering team within the group of Prof. Martin Loess

This week we're featuring an excerpt from a new book about phages, called The Good Virus. This week we have something special: an excerpt from Tom Ireland’s excellent new book on phages, called The Good Virus. Tom Ireland is a freelance sci

This week Amanda Burkardt, CEO of the new phage therapy company, PHIOGEN (a spinoff of Baylor College of Medicine and based on the innovations of TAILOR Labs) shares their plans for the company. ## A Global Vision of an Infection-free Human

This month, we really put the CAPS lock in Capsid: from ORACLE to a CARB-X article on SNIPR, to AKTA and DBs, we really capitalized on many deep topics. Hi everyone, we’re sailing through 2023! These past few weeks has seen Jessica spending

This week, Adam Yang of Lake Forest Academy explores secondary bacterial infections behind COVID-19 deaths, and discusses how phage therapy may be used as a solution. ## Summary While most people solely blame the physiological damage and t

There's still too little data on phage-bacteria biology to support scalable therapeutic phage development. This week, Kayla Young of Phase Genomics tells us how proximity ligation-based metagenomic sequencing is enabling the world’s first c