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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesSep 25, 2020

    Viperins are known to function in the eukaryotic antiviral response, and now they've been found in prokaryotes. Aude Bernheim

    Viperins are known to function in the eukaryotic antiviral response, and now they've been found in prokaryotes. Aude Bernheim (Weizmann Institute of Science) and colleagues published a new paper in Nature on prokaryotic viperins, which prot

    UpdatesPhage defense systemsResearch paper
  2. UpdatesSep 25, 2020

    The use and selection of excipients are critical to stabilize phages in solid formulations. Yajie Zhang (University of Texas

    The use and selection of excipients are critical to stabilize phages in solid formulations. Yajie Zhang (University of Texas at Austin) and colleagues have reviewed the current classes of phage excipients, outstanding challenges with phage

    UpdatesPhage methodsResearch paper
  3. UpdatesSep 25, 2020

    Niels Vander Elst (Ghent University) and colleagues published a new paper in Antibiotics on the characterization of two phage

    Niels Vander Elst (Ghent University) and colleagues published a new paper in Antibiotics on the characterization of two phage lysins, PlySs2 and PlySs9, which have in vitro lytic activity against bovine mastitis pathogen Streptococcus uberi

    UpdatesLysinsResearch paperVeterinary medicine
  4. UpdatesSep 25, 2020

    What's the prevalence of antibiotic resistance genes and virulence genes in complete/near-complete phage genomes? The Millard

    What's the prevalence of antibiotic resistance genes and virulence genes in complete/near-complete phage genomes? The Millard Lab did an analysis; here are the results.

    UpdatesBioinformatics
  5. UpdatesSep 25, 2020

    Clément Girardot wrote a new piece on phage therapy for The Guardian's Global Development section; in it he interviews Tobi N

    Clément Girardot wrote a new piece on phage therapy for The Guardian's Global Development section; in it he interviews Tobi Nagel and Martha Clokie of Phages for Global Health.

    UpdatesGlobal healthNewsPhage Therapy
  6. UpdatesSep 25, 2020

    Micreos has initiated a clinical trial to evaluate a topically-applied phage endolysin as a therapy for Atopic Dermatitis.

    Micreos has initiated a clinical trial to evaluate a topically-applied phage endolysin as a therapy for Atopic Dermatitis.

    UpdatesBiotech newsClinical TrialPhage Therapy
  7. UpdatesSep 25, 2020

    The Central Institute of Brackishwater Aquaculture, an Indian research institute, has been developing phage cocktails for aqu

    The Central Institute of Brackishwater Aquaculture, an Indian research institute, has been developing phage cocktails for aquaculture. They've now transferred their phage technology to Salem Microbes Private Ltd, so it can be made available

    UpdatesAquacultureBiotech news
  8. UpdatesSep 25, 2020

    An international team of scientists are calling for the European Union to enforce non-animal antibody production, and phage d

    An international team of scientists are calling for the European Union to enforce non-animal antibody production, and phage display may be the ideal replacement. Report | Press release.

    UpdatesPhage displayRegulation
  9. UpdatesSep 25, 2020

    The next rendition of PHAVES will be a seminar/Q&A with Dr. Emma Bell, Principal Bacteriophage Scientist at FixedPhage, and w

    The next rendition of PHAVES will be a seminar/Q&A with Dr. Emma Bell, Principal Bacteriophage Scientist at FixedPhage, and will take place October 6th at 4PM GMT+1. She'll discuss their phage immobilization technology and how they've impro

    UpdatesCommunityPHAVESVirtual Event
  10. UpdatesSep 18, 2020

    Hello fellow phage workers - are you modifying phages, genetically or chemically, to improve their ability to act as therapeu

    Hello fellow phage workers - are you modifying phages, genetically or chemically, to improve their ability to act as therapeutics? Attaching toxins so the phage capsid provides specificity to target bacteria? Creating phage based vaccines?

    UpdatesCommunitySpecial Issue
  11. UpdatesSep 18, 2020

    Hi everybody, would anyone be kind enough to share bacterial strain BLT5403? It's part of Novagen's T7 phage kit. Unfortunate

    Hi everybody, would anyone be kind enough to share bacterial strain BLT5403? It's part of Novagen's T7 phage kit. Unfortunately it didn't make the move with me and I don't want to buy a whole kit to just get the bacteria. — @Kean_Research v

    UpdatesCommunityStrain request
  12. UpdatesSep 18, 2020

    The longest river of India, the Ganges, is reported for the richest diversity of bacteriophages compared to any other river a

    The longest river of India, the Ganges, is reported for the richest diversity of bacteriophages compared to any other river across the globe. This diversity was formed when bacteriophages were trapped at the origin of the river millions of

    UpdatesCommunityCommunity messageNew sources of phages
  13. UpdatesSep 18, 2020

    Lorenz Leitner (Balgrist University Hospital, Switzerland) and colleagues published a new paper in The Lancet Infectious Dise

    Lorenz Leitner (Balgrist University Hospital, Switzerland) and colleagues published a new paper in The Lancet Infectious Diseases on the results of a randomised, placebo-controlled, double-blind clinical trial to investigate intravesical ph

    UpdatesClinical TrialPhage TherapyResearch paper
  14. UpdatesSep 18, 2020

    Tao Zuo (The Chinese University of Hong Kong) and collegues published a new paper in Cell Host & Microbe on the fecal DNA vir

    Tao Zuo (The Chinese University of Hong Kong) and collegues published a new paper in Cell Host & Microbe on the fecal DNA virome of 930 healthy adults from two regions in China spanning six ethnicities, including urban and rural residents.

    UpdatesGut viromeResearch paper
  15. UpdatesSep 18, 2020

    Jānis Rūmnieks (Latvian Biomedical Research and Study Center, Latvia) and colleagues published a new paper in Science Advance

    Jānis Rūmnieks (Latvian Biomedical Research and Study Center, Latvia) and colleagues published a new paper in Science Advances showing the 3D structure of 22 uncultured ssRNA phages.

    UpdatesResearch paperStructural Biology
  16. UpdatesSep 18, 2020

    Kaat Schroven (KU Leuven, Belgium) and colleagues published a new review in FEMS Microbiology Reviews on phages as drivers of

    Kaat Schroven (KU Leuven, Belgium) and colleagues published a new review in FEMS Microbiology Reviews on phages as drivers of bacterial virulence and their potential for biotechnological exploitation.

    UpdatesPhage-host interactionsReview
  17. UpdatesSep 18, 2020

    Alejandro González-Mora (Tecnologico de Monterrey, Mexico) and colleagues published a new review in Vaccines on phage-based v

    Alejandro González-Mora (Tecnologico de Monterrey, Mexico) and colleagues published a new review in Vaccines on phage-based vaccines for antigen delivery.

    UpdatesPhage-based vaccinesReview
  18. UpdatesSep 17, 2020

    In silico Phage Hunting: Bioinformatics Exercises to Identify and Explore Bacteriophage Genomes

    This teaching module uses PHASTER and other freely available tools for phage genome identification and phylogenetic analysis in undergraduate microbiology courses. The exercises were field-tested in classes and undergraduate directed resear

    UpdatesPapersBioinformaticsPhage Biology
  19. UpdatesSep 11, 2020

    The next rendition of PHAVES will be a seminar with Dr. Panos Kalatzis (University of Copenhagen) on Sept 22 at 11:00 AM East

    The next rendition of PHAVES will be a seminar with Dr. Panos Kalatzis (University of Copenhagen) on Sept 22 at 11:00 AM Eastern / 5:00 PM (GMT+2). Panos will tell us about the potential of phage therapy in aquaculture. Small group networki

    UpdatesCommunityPHAVESVirtual Event
  20. UpdatesSep 11, 2020

    Elections for the International Society for Viruses of Microorganisms (ISVM) Officers will take place in October 2020. We are

    Elections for the International Society for Viruses of Microorganisms (ISVM) Officers will take place in October 2020. We are still looking for more candidates who wish to serve on the ISVM Board and are extending the candidate application

    UpdatesCommunityElectionISVM
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