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Kate Harding (University of Otago) and colleagues published a new paper on genome-wide identification of bacterial genes for nucleus-forming phage infection, showing flagella and lipopolysaccharide biosynthesis genes are major contributors

Sisi Lin (Shanghai Jiao Tong University) and colleagues published a new paper on coating phage-infected bacteria with polymers, showing this preserves phage vitality and improves therapeutic outcomes in mouse models of bacterial infection c

Zachary Baker (Virginia Tech) and colleagues published a new paper on engineered phages for gut protein delivery, showing that T4 phages can be modified to express therapeutic proteins released during bacterial lysis in the mammalian gut, r

Richard Henshaw (Tufts University) and colleagues published a new paper on chemotaxis of marine bacteria toward virus-infected cyanobacteria, showing that metabolites released during phage infection attract heterotrophic bacteria, likely in

Maciej Żaczek (Hirszfeld Institute of Immunology and Experimental Therapy) and colleagues published a new paper on Polish perceptions of phage therapy, showing awareness of phage therapy varies significantly by education level, with 84.4% o

Tanita Wein (Weizmann Institute of Science) and colleagues published a new paper on bacterial CARD domains in anti-phage defense, showing that CARD domains are essential for protease-mediated activation of bacterial gasdermins that trigger

Siti Adil (La Trobe University) and colleagues published a new phage purification methods comparison paper, showing Triton X-100 was most effective for endotoxin removal and phage recovery compared to CsCl ultracentrifugation and endotoxin

M. Fernanda Vieira (University of Minho) and colleagues published a new paper on machine learning for phage depolymerase identification, showing PhageDPO achieves 96% accuracy in predicting depolymerases with potential biotechnological appl

Rebecca Tarnopol (University of California, Berkeley) and colleagues published a new paper on experimental horizontal gene transfer in Drosophila, showing that phage-derived genes confer innate immunity against parasitoid wasps when express

Antoine Culot (Rime Bioinformatics) and colleagues published a new paper on high-performance phage genome annotation, showing their automated rTOOLS pipeline provides functional annotations comparable to manual methods, enabling safer and f

Benjamin Adler (University of California, Berkeley) and colleagues published CRISPRi-ART for phage functional genomics, a new broad-spectrum phage functional genomics platform. It leverages RNA-targeting dCas13d to selectively interfere wit

Cheng Lu (South China University of Technology) and colleagues published a new paper on synthesizing headful packaging phages, showing functional phages can be synthesized using yeast transformation-associated recombination with only a unit

Eugen Pfeifer (Université Paris-Saclay) and colleagues published a new paper on the impact of cephalosporin antibiotics on gut phages, showing cephalosporins induce phage bursts, mostly of virulent phages, which may help restore microbial d

Brittany Supina (University of Alberta) and colleagues published a new paper on flagella-dependent jumbo phage controlling rice seedling rot, showing a phage that reduces Burkholderia glumae virulence in rice seedlings and depends on bacter

Alexa Fitzpatrick (University of Toronto) and colleagues published a new paper on phage reprogramming of bacterial metabolism, showing two phage proteins increase amino acid and putrescine levels in Pseudomonas aeruginosa to promote efficie

Sada Raza (Institute of Physical Chemistry, Polish Academy of Sciences) and colleagues published a new paper on indigo carmine as an antiphage agent, showing it selectively inactivates DNA phages by binding to their genome and causing capsi

Kat Pick (University of Alberta) and colleagues published a new paper on a novel phage-inducible chromosomal island in E. coli, showing it aids helper phage replication and represses a pathogenicity island.

Landon Getz (University of Toronto) and colleagues published a new paper on integrons as anti-phage defence libraries, showing integrons in Vibrio parahaemolyticus contain diverse anti-phage defence systems, including 9 previously unrecogni

Owen Tuck (University of California, Berkeley) and colleagues published a new paper on Hachiman antiphage defense complex, showing Hachiman is a nuclease-helicase complex that senses genome integrity and degrades DNA upon detecting damage,

Susu Jiang, Chau Chen (Shenzhen University Medical School) and colleagues published a new paper on how a phage-encoded kinase phosphorylates multiple host defense systems including DndFGH and CRISPR-Cas to enable infection.