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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesDec 22, 2023

    Yue Clare Lou and colleagues from the University of California, Berkeley, published a new study on the persistence of infant

    Yue Clare Lou and colleagues from the University of California, Berkeley, published a new study on the persistence of infant gut DNA phage strains during the first 3 years of life.

    UpdatesInfant gut phageomePersistenceResearch paper
  2. UpdatesDec 22, 2023

    Alan Schmalstig (University of North Carolina at Chapel Hill) and colleagues published a new paper on phage infection and kil

    Alan Schmalstig (University of North Carolina at Chapel Hill) and colleagues published a new paper on phage infection and killing of intracellular Mycobacterium abscessus.

    UpdatesIntracellularPhage-host interactionsResearch paper
  3. UpdatesDec 15, 2023

    Han Altae-Tran (Howard Hughes Medical Institute) and colleagues discovered over 200 new CRISPR-associated systems, including

    Han Altae-Tran (Howard Hughes Medical Institute) and colleagues discovered over 200 new CRISPR-associated systems, including Cas14, an enzyme that cuts RNA precisely.

    UpdatesResearch PaperCRISPR
  4. UpdatesDec 15, 2023

    Shinwon Lee (Pusan National University Hospital, Korea) and colleagues conducted a survey revealing that Korean infectious di

    Shinwon Lee (Pusan National University Hospital, Korea) and colleagues conducted a survey revealing that Korean infectious disease specialists are receptive to phage therapy.

    UpdatesPhage TherapyKorean Infectious Diseases SpecialistsResearch Paper
  5. UpdatesDec 8, 2023

    Phages in space!! Phil Huss (University of Wisconsin-Madison) and colleagues discovered that phage-host interactions in micro

    Phages in space!! Phil Huss (University of Wisconsin-Madison) and colleagues discovered that phage-host interactions in microgravity onboard the International Space Station have unique dynamics. They saw significant differences in mutationa

    UpdatesResearch paperPhage in spacePhage-host interactions
  6. UpdatesDec 8, 2023

    Ana Georgina Cobián Güemes (University of California San Diego) and colleagues discovered that jumbo phages are effective aga

    Ana Georgina Cobián Güemes (University of California San Diego) and colleagues discovered that jumbo phages are effective against extensively drug-resistant (XDR) Pseudomonas aeruginosa infections in contaminated preservative-free eyedrops.

    UpdatesResearch PaperJumbo phagesEyedrop outbreak
  7. UpdatesDec 8, 2023

    Abdulkerim Karaynir (Recombinant DNA and Recombinant Protein Center, Turkey) and colleagues have demonstrated the successful

    Abdulkerim Karaynir (Recombinant DNA and Recombinant Protein Center, Turkey) and colleagues have demonstrated the successful transformation of environmental DNA into an active phage in E. coli.

    UpdatesPhage rebootingSynthetic biologyResearch paper
  8. UpdatesDec 1, 2023

    If you are using iPHoP for phage host prediction: a new update has just been released (1.3.3), alongside an updated host data

    If you are using iPHoP for phage host prediction: a new update has just been released (1.3.3), alongside an updated host database now based on GTDB r214. Updated code and database available via conda / Docker. Report any issues here.

    UpdatesCommunityResearch PaperPhage-Host PredictionGenomic Analysis
  9. UpdatesDec 1, 2023

    Tired of doing plaque assays? Check out the Bollyky lab’s new method to count phages and assess their bioactivity using a DLS

    Tired of doing plaque assays? Check out the Bollyky lab’s new method to count phages and assess their bioactivity using a DLS Particle Size Analyzer, now published in PNAS. Great tweet thread here!

    UpdatesResearch PaperDynamic Light ScatteringPhage methods
  10. UpdatesDec 1, 2023

    Baptiste Gaborieau (Université Paris Cité, France) and colleagues published a new preprint on predicting diverse phage bacter

    Baptiste Gaborieau (Université Paris Cité, France) and colleagues published a new preprint on predicting diverse phage bacteria-interactions at the strain level from their genomes only. They created a matrix of >38k phage-bacteria interacti

    UpdatesResearch PaperPhage InteractionsPredictive Algorithms
  11. JobsNov 24, 2023

    The Le Roux lab at the Université de Montréal is hiring a postdoc in Microbial Genomics to investigate Vibrio phage-bacteria

    The Le Roux lab at the Université de Montréal is hiring a postdoc in Microbial Genomics to investigate Vibrio phage-bacteria coevolution and phage satellites.

    JobsPostdocMicrobial GenomicsResearch Paper
  12. UpdatesNov 24, 2023

    Justin Boeckman (Center for Phage Technology, Texas) and colleagues published a protocol detailing methods for phage DNA extr

    Justin Boeckman (Center for Phage Technology, Texas) and colleagues published a protocol detailing methods for phage DNA extraction, genome assembly, and genome closure.

    UpdatesResearch PaperMethodsDNA ExtractionGenome Assembly
  13. UpdatesNov 24, 2023

    Erez Yirmiya (Weizmann Institute of Science, Israel) and colleagues analyzed groups of closely related Bacillus phages that s

    Erez Yirmiya (Weizmann Institute of Science, Israel) and colleagues analyzed groups of closely related Bacillus phages that showed differential sensitivity to bacterial defense systems, and discovered four distinct families of anti-defense

    UpdatesAnti-Defence ProteinsBacterial ImmunityResearch Paper
  14. UpdatesNov 17, 2023

    Guy Mason and colleagues found that E. coli can persistently grow during phage predation in spatially confined environments.

    Guy Mason and colleagues found that E. coli can persistently grow during phage predation in spatially confined environments.

    UpdatesResearch PaperMechanosensingPhage-host interactions
  15. UpdatesNov 17, 2023

    Mikhail Skutel and colleagues demonstrate how the T5-like phage BF23 evades host-mediated DNA restriction and methylation.

    Mikhail Skutel and colleagues demonstrate how the T5-like phage BF23 evades host-mediated DNA restriction and methylation.

    UpdatesResearch PaperPhage defense
  16. UpdatesNov 17, 2023

    Jumpei Fujiki and colleagues explore the fitness trade-offs between phage and antibiotic sensitivity in phage-resistant varia

    Jumpei Fujiki and colleagues explore the fitness trade-offs between phage and antibiotic sensitivity in phage-resistant variants.

    UpdatesResearch PaperPhage-host interactionsPhage-antibiotic synergy
  17. UpdatesNov 17, 2023

    Mohammad Hashem Yousefi (KU Leuven) and colleagues have isolated and characterized a novel Salmonella Typhimurium phage calle

    Mohammad Hashem Yousefi (KU Leuven) and colleagues have isolated and characterized a novel Salmonella Typhimurium phage called Arash, a novel species in the novel ‘Arashvirus’ genus, from hospital wastewater.

    UpdatesResearch paperPhage characterization
  18. UpdatesNov 3, 2023

    Tagide deCarvalho and colleagues at the University of Maryland, Baltimore County have imaged a satellite phage attaching to a

    Tagide deCarvalho and colleagues at the University of Maryland, Baltimore County have imaged a satellite phage attaching to another phage. Check out their paper, where they’ve described two novel satellite-helper phage systems, Mulch and Fl

    UpdatesResearch paperMicroscopySatellite phages
  19. UpdatesNov 3, 2023

    The newest issue of Clinical Infectious Diseases features a special collection of articles exploring various aspects of phage

    The newest issue of Clinical Infectious Diseases features a special collection of articles exploring various aspects of phage therapy, including standardization of phage susceptibility testing, phage annotation and nomenclature, advanced ma

    UpdatesClinical Infectious DiseaseResearch Paper
  20. UpdatesNov 3, 2023

    Marion Bichet (Monash University, Australia) and colleagues found that phage T4 can enhance growth and survival of mammalian

    Marion Bichet (Monash University, Australia) and colleagues found that phage T4 can enhance growth and survival of mammalian cells, shedding light on the potential symbiotic interactions between phages and their hosts.

    UpdatesResearch PaperMammalian Cells
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