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Felix Croteau (McMaster University) and colleagues published a new paper on phage environmental DNA enhancing CRISPR adaptation, showing that free phage DNA in lysates increases phage-insensitive mutant generation through natural competence

Mary Eliza (Helmholtz Centre for Environmental Research, Germany) and colleagues published a new paper exploring the influence of a prophage on two different strains of rhizobia during their symbiosis with legumes. They show that while in o

Amaury Bignaud (Institut Pasteur) and colleagues published a new paper on broad host range phages across ecosystems, showing that multihost phage associations are common in diverse environments, challenging the traditional narrow host spect

Shelby Andersen (University of Colorado Anschutz Medical Campus) and colleagues published a new paper on systematic phage gene function interrogation, showing PhageMaP enables high-throughput screening of phage mutant libraries to decipher

Zhiying Zhang (Memorial Sloan Kettering Cancer Center) and colleagues published a new paper on a membrane-embedded Kiwa defense supercomplex mechanism, showing KwaA and KwaB form transmembrane complexes that detect phage attachment and bind

Hannah Kapoor (Oregon State University) and colleagues published a new paper on phage-mediated TLR2 signaling against intracellular Mycobacterium abscessus, showing certain mycobacteriophages stimulate TLR2 signaling and NLRP3 inflammasome

Amit Vikram (Intralytix) and colleagues published a new paper on phage cocktail biocontrol in wheat milling operations, showing significant E. coli O157:H7 reductions of 1.4-3.1 log CFU/g without affecting flour quality or baking properties

Jérémy Cherbuin (Lausanne University Hospital) and colleagues published a new paper on in vivo podovirus resistance via tarS mutations, showing tarS disruption causes phage 66 resistance in MSSA endocarditis through impaired wall teichoic a

Jiayu Gu (Chinese Academy of Sciences) and colleagues published a new paper on crosstalk between inovirus core gene and accessory toxin-antitoxin system, showing RepG4 protein from Pf4 phage triggers degradation of PfpC antitoxin, coordinat

Matt Walker (Columbia University) and colleagues published a new paper on RNA-guided flagellar remodeling by temperate phages, showing prophages use TldR transcription factors to alter host flagellar composition, enhancing bacterial motilit

Sophia Zborowsky (Institut Pasteur) and colleagues published a new paper on macrophage interference with phage therapy efficacy, showing alveolar macrophages reduce phage density through phagocytosis and adsorption inhibition, limiting ther

Mengyu Li (University of Sydney) and colleagues published a new paper on long-term stability of inhalable phage powder formulations, showing spray-dried phage powders maintained viability over four years with 0.97-2.49 log titer reduction,

Zainab Dere (Florida State University) and colleagues published a new paper on optimal phage therapy control strategies, showing mathematically that phages can suppress antibiotic-resistant bacteria and offering a clinically translatable im

Naïma Madi (McGill University) and colleagues published a new paper on ranking phage predation as dehydration determinant, showing the phage-to-pathogen ratio is a top classifier of severe dehydration in cholera patients, just behind age an

Clara Torres-Barceló (University of Montpellier) and colleagues introduce the Phylogenetic Host-Range Index (PHRI) — a new metric to classify phages as specialists or generalists based on bacterial genetic diversity. Using phages infecting

Chujin Ruan (Swiss Federal Institute of Aquatic Science and Technology (Eawag)) and colleagues published a new paper on how phage-mediated peripheral kill-the-winner facilitates the maintenance of costly antibiotic resistance.

Afif Jati (Monash University) and colleagues published a new paper in npj Viruses on how highly stable phages PIN1 and PIN2 have hallmarks of flagellotropic phages but infect immotile bacteria.

Marina Mahler (University of Otago) and colleagues published a new paper on arabinosyl-hydroxy-cytosine DNA modifications, showing that these modifications enable phages to evade DNA-targeting CRISPR-Cas and restriction systems while remain

Per Kristian Thorén Edvardsen (Norwegian University of Life Sciences) and colleagues published a new paper on a cryptic prophage endolysin with muramidase activity. They solve its crystal structure and show 10,000-fold higher activity than

Xiang Hou (Shanghai Jiao Tong University School of Medicine) and colleagues published a new paper on gut phage-induced macrophage reprogramming, showing phages epigenetically prime macrophages via IL-10 to generate LPS-tolerant innate memor